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Inhibition of Btk by Btk-specific concentrations of ibrutinib and acalabrutinib delays but does not block platelet aggregation mediated by glycoprotein VI.
Nicolson PLR, Hughes CE, Watson S, Nock SH, Hardy AT, Watson CN, Montague SJ, Clifford H, Huissoon AP, Malcor JD, Thomas MR, Pollitt AY, Tomlinson MG, Pratt G, Watson SP. Nicolson PLR, et al. Among authors: watson cn, watson sp, watson s. Haematologica. 2018 Dec;103(12):2097-2108. doi: 10.3324/haematol.2018.193391. Epub 2018 Jul 19. Haematologica. 2018. PMID: 30026342 Free PMC article.
Salmonella-induced thrombi in mice develop asynchronously in the spleen and liver and are not effective bacterial traps.
Beristain-Covarrubias N, Perez-Toledo M, Flores-Langarica A, Zuidscherwoude M, Hitchcock JR, Channell WM, King LDW, Thomas MR, Henderson IR, Rayes J, Watson SP, Cunningham AF. Beristain-Covarrubias N, et al. Among authors: watson sp. Blood. 2019 Feb 7;133(6):600-604. doi: 10.1182/blood-2018-08-867267. Epub 2018 Nov 6. Blood. 2019. PMID: 30401709 Free PMC article.
Understanding Infection-Induced Thrombosis: Lessons Learned From Animal Models.
Beristain-Covarrubias N, Perez-Toledo M, Thomas MR, Henderson IR, Watson SP, Cunningham AF. Beristain-Covarrubias N, et al. Among authors: watson sp. Front Immunol. 2019 Nov 5;10:2569. doi: 10.3389/fimmu.2019.02569. eCollection 2019. Front Immunol. 2019. PMID: 31749809 Free PMC article. Review.
Low-dose Btk inhibitors selectively block platelet activation by CLEC-2.
Nicolson PLR, Nock SH, Hinds J, Garcia-Quintanilla L, Smith CW, Campos J, Brill A, Pike JA, Khan AO, Poulter NS, Kavanagh DM, Watson S, Watson CN, Clifford H, Huissoon AP, Pollitt AY, Eble JA, Pratt G, Watson SP, Hughes CE. Nicolson PLR, et al. Among authors: watson cn, watson sp, watson s. Haematologica. 2021 Jan 1;106(1):208-219. doi: 10.3324/haematol.2019.218545. Haematologica. 2021. PMID: 31949019 Free PMC article.
Antiprothrombin antibodies induce platelet activation: A possible explanation for anti-FXa therapy failure in patients with antiphospholipid syndrome?
Chayoua W, Nicolson PLR, Meijers JCM, Kardeby C, Garcia-Quintanilla L, Devreese KMJ, de Laat B, Watson SP, de Groot PG. Chayoua W, et al. Among authors: watson sp. J Thromb Haemost. 2021 Jul;19(7):1776-1782. doi: 10.1111/jth.15320. Epub 2021 May 5. J Thromb Haemost. 2021. PMID: 33774918 Free PMC article.
493 results