Tate EW - Search Results

1

A Probe for NLRP3 Inflammasome Inhibitor MCC950 Identifies Carbonic Anhydrase 2 as a Novel Target.

Kennedy CR, Goya Grocin A, Kovačič T, Singh R, Ward JA, Shenoy AR, Tate EW. Kennedy CR, et al. Among authors: tate ew. ACS Chem Biol. 2021 Jun 18;16(6):982-990. doi: 10.1021/acschembio.1c00218. Epub 2021 May 18. ACS Chem Biol. 2021. PMID: 34003636 Free PMC article.

2

Chemical probes of surface layer biogenesis in Clostridium difficile.

Dang TH, de la Riva L, Fagan RP, Storck EM, Heal WP, Janoir C, Fairweather NF, Tate EW. Dang TH, et al. Among authors: tate ew. ACS Chem Biol. 2010 Mar 19;5(3):279-85. doi: 10.1021/cb9002859. ACS Chem Biol. 2010. PMID: 20067320 Free article.

3

Crystal structures of stapled and hydrogen bond surrogate peptides targeting a fully buried protein-helix interaction.

Douse CH, Maas SJ, Thomas JC, Garnett JA, Sun Y, Cota E, Tate EW. Douse CH, et al. Among authors: tate ew. ACS Chem Biol. 2014 Oct 17;9(10):2204-9. doi: 10.1021/cb500271c. Epub 2014 Aug 6. ACS Chem Biol. 2014. PMID: 25084543 Free article.

4

Target profiling of zerumbone using a novel cell-permeable clickable probe and quantitative chemical proteomics.

Kalesh KA, Clulow JA, Tate EW. Kalesh KA, et al. Among authors: tate ew. Chem Commun (Camb). 2015 Mar 28;51(25):5497-500. doi: 10.1039/c4cc09527h. Chem Commun (Camb). 2015. PMID: 25598414 Free article.

5

N-Myristoyltransferase Inhibition Induces ER-Stress, Cell Cycle Arrest, and Apoptosis in Cancer Cells.

Thinon E, Morales-Sanfrutos J, Mann DJ, Tate EW. Thinon E, et al. Among authors: tate ew. ACS Chem Biol. 2016 Aug 19;11(8):2165-76. doi: 10.1021/acschembio.6b00371. Epub 2016 Jun 7. ACS Chem Biol. 2016. PMID: 27267252 Free PMC article.

6

Quantitative Chemical Proteomic Profiling of Ubiquitin Specific Proteases in Intact Cancer Cells.

Ward JA, McLellan L, Stockley M, Gibson KR, Whitlock GA, Knights C, Harrigan JA, Jacq X, Tate EW. Ward JA, et al. Among authors: tate ew. ACS Chem Biol. 2016 Dec 16;11(12):3268-3272. doi: 10.1021/acschembio.6b00766. Epub 2016 Oct 31. ACS Chem Biol. 2016. PMID: 27779380 Free article.

7

Characterization of Hedgehog Acyltransferase Inhibitors Identifies a Small Molecule Probe for Hedgehog Signaling by Cancer Cells.

Rodgers UR, Lanyon-Hogg T, Masumoto N, Ritzefeld M, Burke R, Blagg J, Magee AI, Tate EW. Rodgers UR, et al. Among authors: tate ew. ACS Chem Biol. 2016 Dec 16;11(12):3256-3262. doi: 10.1021/acschembio.6b00896. Epub 2016 Oct 25. ACS Chem Biol. 2016. PMID: 27779865 Free PMC article.

8

N-Myristoylation as a Drug Target in Malaria: Exploring the Role of N-Myristoyltransferase Substrates in the Inhibitor Mode of Action.

Schlott AC, Holder AA, Tate EW. Schlott AC, et al. Among authors: tate ew. ACS Infect Dis. 2018 Apr 13;4(4):449-457. doi: 10.1021/acsinfecdis.7b00203. Epub 2018 Feb 2. ACS Infect Dis. 2018. PMID: 29363940 Free article. Review.

9

Whole Proteome Profiling of N-Myristoyltransferase Activity and Inhibition Using Sortase A.

Goya Grocin A, Serwa RA, Morales Sanfrutos J, Ritzefeld M, Tate EW. Goya Grocin A, et al. Among authors: tate ew. Mol Cell Proteomics. 2019 Jan;18(1):115-126. doi: 10.1074/mcp.RA118.001043. Epub 2018 Oct 19. Mol Cell Proteomics. 2019. PMID: 30341083 Free PMC article.

10

Validation and Invalidation of Chemical Probes for the Human N-myristoyltransferases.

Kallemeijn WW, Lueg GA, Faronato M, Hadavizadeh K, Goya Grocin A, Song OR, Howell M, Calado DP, Tate EW. Kallemeijn WW, et al. Among authors: tate ew. Cell Chem Biol. 2019 Jun 20;26(6):892-900.e4. doi: 10.1016/j.chembiol.2019.03.006. Epub 2019 Apr 18. Cell Chem Biol. 2019. PMID: 31006618 Free PMC article.

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