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PKM2-dependent metabolic skewing of hepatic Th17 cells regulates pathogenesis of non-alcoholic fatty liver disease.
Moreno-Fernandez ME, Giles DA, Oates JR, Chan CC, Damen MSMA, Doll JR, Stankiewicz TE, Chen X, Chetal K, Karns R, Weirauch MT, Romick-Rosendale L, Xanthakos SA, Sheridan R, Szabo S, Shah AS, Helmrath MA, Inge TH, Deshmukh H, Salomonis N, Divanovic S. Moreno-Fernandez ME, et al. Among authors: chan cc. Cell Metab. 2021 Jun 1;33(6):1187-1204.e9. doi: 10.1016/j.cmet.2021.04.018. Epub 2021 May 17. Cell Metab. 2021. PMID: 34004162 Free PMC article.
Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling.
Giles DA, Moreno-Fernandez ME, Stankiewicz TE, Graspeuntner S, Cappelletti M, Wu D, Mukherjee R, Chan CC, Lawson MJ, Klarquist J, Sünderhauf A, Softic S, Kahn CR, Stemmer K, Iwakura Y, Aronow BJ, Karns R, Steinbrecher KA, Karp CL, Sheridan R, Shanmukhappa SK, Reynaud D, Haslam DB, Sina C, Rupp J, Hogan SP, Divanovic S. Giles DA, et al. Among authors: chan cc. Nat Med. 2017 Jul;23(7):829-838. doi: 10.1038/nm.4346. Epub 2017 Jun 12. Nat Med. 2017. PMID: 28604704 Free PMC article.
Inflammation and Immunity: From an Adipocyte's Perspective.
Chan CC, Damen MSMA, Alarcon PC, Sanchez-Gurmaches J, Divanovic S. Chan CC, et al. J Interferon Cytokine Res. 2019 Aug;39(8):459-471. doi: 10.1089/jir.2019.0014. Epub 2019 Mar 28. J Interferon Cytokine Res. 2019. PMID: 30920343 Free PMC article. Review.
Type I interferon sensing unlocks dormant adipocyte inflammatory potential.
Chan CC, Damen MSMA, Moreno-Fernandez ME, Stankiewicz TE, Cappelletti M, Alarcon PC, Oates JR, Doll JR, Mukherjee R, Chen X, Karns R, Weirauch MT, Helmrath MA, Inge TH, Divanovic S. Chan CC, et al. Nat Commun. 2020 Jun 2;11(1):2745. doi: 10.1038/s41467-020-16571-4. Nat Commun. 2020. PMID: 32488081 Free PMC article.
A BAFF/APRIL axis regulates obesogenic diet-driven weight gain.
Chan CC, Harley ITW, Pfluger PT, Trompette A, Stankiewicz TE, Allen JL, Moreno-Fernandez ME, Damen MSMA, Oates JR, Alarcon PC, Doll JR, Flick MJ, Flick LM, Sanchez-Gurmaches J, Mukherjee R, Karns R, Helmrath M, Inge TH, Weisberg SP, Pamp SJ, Relman DA, Seeley RJ, Tschöp MH, Karp CL, Divanovic S. Chan CC, et al. Nat Commun. 2021 May 18;12(1):2911. doi: 10.1038/s41467-021-23084-1. Nat Commun. 2021. PMID: 34006859 Free PMC article.
Hepatic Ago2-mediated RNA silencing controls energy metabolism linked to AMPK activation and obesity-associated pathophysiology.
Zhang C, Seo J, Murakami K, Salem ESB, Bernhard E, Borra VJ, Choi K, Yuan CL, Chan CC, Chen X, Huang T, Weirauch MT, Divanovic S, Qi NR, Thomas HE, Mercer CA, Siomi H, Nakamura T. Zhang C, et al. Among authors: chan cc. Nat Commun. 2018 Sep 10;9(1):3658. doi: 10.1038/s41467-018-05870-6. Nat Commun. 2018. PMID: 30201950 Free PMC article.
Erratum: Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling.
Giles DA, Moreno-Fernandez ME, Stankiewicz TE, Graspeuntner S, Cappelletti M, Wu D, Mukherjee R, Chan CC, Lawson MJ, Klarquist J, Sünderhauf A, Softic S, Kahn CR, Stemmer K, Iwakura Y, Aronow BJ, Karns R, Steinbrecher KA, Karp CL, Sheridan R, Shanmukhappa SK, Reynaud D, Haslam DB, Sina C, Rupp J, Hogan SP, Divanovic S. Giles DA, et al. Among authors: chan cc. Nat Med. 2017 Oct 6;23(10):1241. doi: 10.1038/nm1017-1241c. Nat Med. 2017. PMID: 28985207
2,015 results