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Repurposing screen identifies novel candidates for broad-spectrum coronavirus antivirals and druggable host targets.
Haid S, Matthaei A, Winkler M, Sake SM, Gunesch AP, Milke V, Köhler NM, Rückert J, Vieyres G, Kühl D, Nguyen T-T, Göhl M, Lasswitz L, Zapatero-Belinchón FJ, Brogden G, Gerold G, Wiegmann B, Bilitewski U, Brown RJP, Brönstrup M, Schulz TF, Pietschmann T. Haid S, et al. Among authors: gohl m. Antimicrob Agents Chemother. 2024 Mar 6;68(3):e0121023. doi: 10.1128/aac.01210-23. Epub 2024 Feb 6. Antimicrob Agents Chemother. 2024. PMID: 38319076 Free PMC article.
Enantioselective Syntheses of Wickerols A and B.
Chung J, Capani JS Jr, Göhl M, Roosen PC, Vanderwal CD. Chung J, et al. Among authors: gohl m. J Am Chem Soc. 2023 Mar 22;145(11):6486-6497. doi: 10.1021/jacs.3c00448. Epub 2023 Mar 8. J Am Chem Soc. 2023. PMID: 36883956 Free PMC article.
Diastereomeric Resolution Yields Highly Potent Inhibitor of SARS-CoV-2 Main Protease.
Cooper MS, Zhang L, Ibrahim M, Zhang K, Sun X, Röske J, Göhl M, Brönstrup M, Cowell JK, Sauerhering L, Becker S, Vangeel L, Jochmans D, Neyts J, Rox K, Marsh GP, Maple HJ, Hilgenfeld R. Cooper MS, et al. Among authors: gohl m. J Med Chem. 2022 Oct 13;65(19):13328-13342. doi: 10.1021/acs.jmedchem.2c01131. Epub 2022 Sep 30. J Med Chem. 2022. PMID: 36179320 Free PMC article.
17 results