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Page 1
Structure-Activity Relationship Studies of Trisubstituted Isoxazoles as Selective Allosteric Ligands for the Retinoic-Acid-Receptor-Related Orphan Receptor γt.
Meijer FA, Saris AOWM, Doveston RG, Oerlemans GJM, de Vries RMJM, Somsen BA, Unger A, Klebl B, Ottmann C, Cossar PJ, Brunsveld L. Meijer FA, et al. Among authors: cossar pj. J Med Chem. 2021 Jul 8;64(13):9238-9258. doi: 10.1021/acs.jmedchem.1c00475. Epub 2021 May 19. J Med Chem. 2021. PMID: 34008974 Free PMC article.
An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-κB-Utilizing a Reversible Covalent Tethering Approach.
Wolter M, Valenti D, Cossar PJ, Hristeva S, Levy LM, Genski T, Hoffmann T, Brunsveld L, Tzalis D, Ottmann C. Wolter M, et al. Among authors: cossar pj. J Med Chem. 2021 Jun 24;64(12):8423-8436. doi: 10.1021/acs.jmedchem.1c00401. Epub 2021 Jun 2. J Med Chem. 2021. PMID: 34076416 Free PMC article.
Covalent flexible peptide docking in Rosetta.
Tivon B, Gabizon R, Somsen BA, Cossar PJ, Ottmann C, London N. Tivon B, et al. Among authors: cossar pj. Chem Sci. 2021 Jul 12;12(32):10836-10847. doi: 10.1039/d1sc02322e. eCollection 2021 Aug 18. Chem Sci. 2021. PMID: 34476063 Free PMC article.
Fragment-based exploration of the 14-3-3/Amot-p130 interface.
Centorrino F, Andlovic B, Cossar P, Brunsveld L, Ottmann C. Centorrino F, et al. Curr Res Struct Biol. 2021 Dec 29;4:21-28. doi: 10.1016/j.crstbi.2021.12.003. eCollection 2022. Curr Res Struct Biol. 2021. PMID: 35036934 Free PMC article.
26 results