O'Grady T - Search Results

1

ERG transcription factors have a splicing regulatory function involving RBFOX2 that is altered in the EWS-FLI1 oncogenic fusion.

Saulnier O, Guedri-Idjouadiene K, Aynaud MM, Chakraborty A, Bruyr J, Pineau J, O'Grady T, Mirabeau O, Grossetête S, Galvan B, Claes M, Al Oula Hassoun Z, Sadacca B, Laud K, Zaïdi S, Surdez D, Baulande S, Rambout X, Tirode F, Dutertre M, Delattre O, Dequiedt F. Saulnier O, et al. Nucleic Acids Res. 2021 May 21;49(9):5038-5056. doi: 10.1093/nar/gkab305. Nucleic Acids Res. 2021. PMID: 34009296 Free PMC article.

2

Dephosphorylation of HDAC4 by PP2A-Bδ unravels a new role for the HDAC4/MEF2 axis in myoblast fusion.

Veloso A, Martin M, Bruyr J, O'Grady T, Deroanne C, Mottet D, Twizere JC, Cherrier T, Dequiedt F. Veloso A, et al. Cell Death Dis. 2019 Jul 4;10(7):512. doi: 10.1038/s41419-019-1743-6. Cell Death Dis. 2019. PMID: 31273193 Free PMC article.

3

The HTLV-1 viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape.

Vandermeulen C, O'Grady T, Wayet J, Galvan B, Maseko S, Cherkaoui M, Desbuleux A, Coppin G, Olivet J, Ben Ameur L, Kataoka K, Ogawa S, Hermine O, Marcais A, Thiry M, Mortreux F, Calderwood MA, Van Weyenbergh J, Peloponese JM, Charloteaux B, Van den Broeke A, Hill DE, Vidal M, Dequiedt F, Twizere JC. Vandermeulen C, et al. PLoS Pathog. 2021 Sep 20;17(9):e1009919. doi: 10.1371/journal.ppat.1009919. eCollection 2021 Sep. PLoS Pathog. 2021. PMID: 34543356 Free PMC article.

4

DHX15-independent roles for TFIP11 in U6 snRNA modification, U4/U6.U5 tri-snRNP assembly and pre-mRNA splicing fidelity.

Duchemin A, O'Grady T, Hanache S, Mereau A, Thiry M, Wacheul L, Michaux C, Perpète E, Hervouet E, Peixoto P, Ernst FGM, Audic Y, Dequiedt F, Lafontaine DLJ, Mottet D. Duchemin A, et al. Nat Commun. 2021 Nov 17;12(1):6648. doi: 10.1038/s41467-021-26932-2. Nat Commun. 2021. PMID: 34789764 Free PMC article.

5

Sorting and packaging of RNA into extracellular vesicles shape intracellular transcript levels.

O'Grady T, Njock MS, Lion M, Bruyr J, Mariavelle E, Galvan B, Boeckx A, Struman I, Dequiedt F. O'Grady T, et al. BMC Biol. 2022 Mar 24;20(1):72. doi: 10.1186/s12915-022-01277-4. BMC Biol. 2022. PMID: 35331218 Free PMC article.

6

Endothelial extracellular vesicles promote tumour growth by tumour-associated macrophage reprogramming.

Njock MS, O'Grady T, Nivelles O, Lion M, Jacques S, Cambier M, Herkenne S, Muller F, Christian A, Remacle C, Guiot J, Rahmouni S, Dequiedt F, Struman I. Njock MS, et al. J Extracell Vesicles. 2022 Jun;11(6):e12228. doi: 10.1002/jev2.12228. J Extracell Vesicles. 2022. PMID: 35656866 Free PMC article.

7

The transcription factor c-Jun inhibits RBM39 to reprogram pre-mRNA splicing during genotoxic stress.

Lemaitre F, Chakrama F, O'Grady T, Peulen O, Rademaker G, Deward A, Chabot B, Piette J, Colige A, Lambert C, Dequiedt F, Habraken Y. Lemaitre F, et al. Nucleic Acids Res. 2022 Dec 9;50(22):12768-12789. doi: 10.1093/nar/gkac1130. Nucleic Acids Res. 2022. PMID: 36477312 Free PMC article.

8

SpliceTools, a suite of downstream RNA splicing analysis tools to investigate mechanisms and impact of alternative splicing.

Flemington EK, Flemington SA, O'Grady TM, Baddoo M, Nguyen T, Dong Y, Ungerleider NA. Flemington EK, et al. Nucleic Acids Res. 2023 Apr 24;51(7):e42. doi: 10.1093/nar/gkad111. Nucleic Acids Res. 2023. PMID: 36864749 Free PMC article.

9

Viral reprogramming of host transcription initiation.

Ungerleider NA, Roberts C, O'Grady TM, Nguyen TT, Baddoo M, Wang J, Ishaq E, Concha M, Lam M, Bass J, Nguyen TD, Van Otterloo N, Wickramarachchige-Dona N, Wyczechowska D, Morales M, Ma T, Dong Y, Flemington EK. Ungerleider NA, et al. Among authors: o grady tm. Nucleic Acids Res. 2024 May 22;52(9):5016-5032. doi: 10.1093/nar/gkae175. Nucleic Acids Res. 2024. PMID: 38471819 Free PMC article.

10

High-density resolution of the Kaposi's sarcoma associated herpesvirus transcriptome identifies novel transcript isoforms generated by long-range transcription and alternative splicing.

Shekhar R, O'Grady T, Keil N, Feswick A, Amador DAM, Tibbetts SA, Flemington EK, Renne R. Shekhar R, et al. Among authors: o grady t. Nucleic Acids Res. 2024 Jul 22;52(13):7720-7739. doi: 10.1093/nar/gkae540. Nucleic Acids Res. 2024. PMID: 38922687 Free PMC article.

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