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Western diet induces Paneth cell defects through microbiome alterations and farnesoid X receptor and type I interferon activation.
Liu TC, Kern JT, Jain U, Sonnek NM, Xiong S, Simpson KF, VanDussen KL, Winkler ES, Haritunians T, Malique A, Lu Q, Sasaki Y, Storer C, Diamond MS, Head RD, McGovern DPB, Stappenbeck TS. Liu TC, et al. Among authors: winkler es. Cell Host Microbe. 2021 Jun 9;29(6):988-1001.e6. doi: 10.1016/j.chom.2021.04.004. Epub 2021 May 18. Cell Host Microbe. 2021. PMID: 34010595 Free PMC article.
Dengue and Zika Virus Cross-Reactive Human Monoclonal Antibodies Protect against Spondweni Virus Infection and Pathogenesis in Mice.
Salazar V, Jagger BW, Mongkolsapaya J, Burgomaster KE, Dejnirattisai W, Winkler ES, Fernandez E, Nelson CA, Fremont DH, Pierson TC, Crowe JE Jr, Screaton GR, Diamond MS. Salazar V, et al. Among authors: winkler es. Cell Rep. 2019 Feb 5;26(6):1585-1597.e4. doi: 10.1016/j.celrep.2019.01.052. Cell Rep. 2019. PMID: 30726740 Free PMC article.
Zika Virus Causes Acute and Chronic Prostatitis in Mice and Macaques.
Halabi J, Jagger BW, Salazar V, Winkler ES, White JP, Humphrey PA, Hirsch AJ, Streblow DN, Diamond MS, Moley K. Halabi J, et al. Among authors: winkler es. J Infect Dis. 2020 Apr 7;221(9):1506-1517. doi: 10.1093/infdis/jiz533. J Infect Dis. 2020. PMID: 31616920 Free PMC article.
A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies.
Hassan AO, Case JB, Winkler ES, Thackray LB, Kafai NM, Bailey AL, McCune BT, Fox JM, Chen RE, Alsoussi WB, Turner JS, Schmitz AJ, Lei T, Shrihari S, Keeler SP, Fremont DH, Greco S, McCray PB Jr, Perlman S, Holtzman MJ, Ellebedy AH, Diamond MS. Hassan AO, et al. Among authors: winkler es. Cell. 2020 Aug 6;182(3):744-753.e4. doi: 10.1016/j.cell.2020.06.011. Epub 2020 Jun 10. Cell. 2020. PMID: 32553273 Free PMC article.
A Potently Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection.
Alsoussi WB, Turner JS, Case JB, Zhao H, Schmitz AJ, Zhou JQ, Chen RE, Lei T, Rizk AA, McIntire KM, Winkler ES, Fox JM, Kafai NM, Thackray LB, Hassan AO, Amanat F, Krammer F, Watson CT, Kleinstein SH, Fremont DH, Diamond MS, Ellebedy AH. Alsoussi WB, et al. Among authors: winkler es. J Immunol. 2020 Aug 15;205(4):915-922. doi: 10.4049/jimmunol.2000583. Epub 2020 Jun 26. J Immunol. 2020. PMID: 32591393 Free PMC article.
The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis.
Winkler ES, Shrihari S, Hykes BL Jr, Handley SA, Andhey PS, Huang YS, Swain A, Droit L, Chebrolu KK, Mack M, Vanlandingham DL, Thackray LB, Cella M, Colonna M, Artyomov MN, Stappenbeck TS, Diamond MS. Winkler ES, et al. Cell. 2020 Aug 20;182(4):901-918.e18. doi: 10.1016/j.cell.2020.06.029. Epub 2020 Jul 14. Cell. 2020. PMID: 32668198 Free PMC article.
SARS-CoV-2 infection in the lungs of human ACE2 transgenic mice causes severe inflammation, immune cell infiltration, and compromised respiratory function.
Winkler ES, Bailey AL, Kafai NM, Nair S, McCune BT, Yu J, Fox JM, Chen RE, Earnest JT, Keeler SP, Ritter JH, Kang LI, Dort S, Robichaud A, Head R, Holtzman MJ, Diamond MS. Winkler ES, et al. bioRxiv [Preprint]. 2020 Jul 10:2020.07.09.196188. doi: 10.1101/2020.07.09.196188. bioRxiv. 2020. PMID: 32676600 Free PMC article. Preprint.
Replication-Competent Vesicular Stomatitis Virus Vaccine Vector Protects against SARS-CoV-2-Mediated Pathogenesis in Mice.
Case JB, Rothlauf PW, Chen RE, Kafai NM, Fox JM, Smith BK, Shrihari S, McCune BT, Harvey IB, Keeler SP, Bloyet LM, Zhao H, Ma M, Adams LJ, Winkler ES, Holtzman MJ, Fremont DH, Whelan SPJ, Diamond MS. Case JB, et al. Among authors: winkler es. Cell Host Microbe. 2020 Sep 9;28(3):465-474.e4. doi: 10.1016/j.chom.2020.07.018. Epub 2020 Jul 30. Cell Host Microbe. 2020. PMID: 32798445 Free PMC article.
47 results