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Patient-derived tumor xenograft and organoid models established from resected pancreatic, duodenal and biliary cancers.
Pham NA, Radulovich N, Ibrahimov E, Martins-Filho SN, Li Q, Pintilie M, Weiss J, Raghavan V, Cabanero M, Denroche RE, Wilson JM, Metran-Nascente C, Borgida A, Hutchinson S, Dodd A, Begora M, Chadwick D, Serra S, Knox JJ, Gallinger S, Hedley DW, Muthuswamy L, Tsao MS. Pham NA, et al. Among authors: li q. Sci Rep. 2021 May 19;11(1):10619. doi: 10.1038/s41598-021-90049-1. Sci Rep. 2021. PMID: 34011980 Free PMC article.
Characterization of Distinct Populations of Carcinoma-Associated Fibroblasts from Non-Small Cell Lung Carcinoma Reveals a Role for ST8SIA2 in Cancer Cell Invasion.
Hao J, Zeltz C, Pintilie M, Li Q, Sakashita S, Wang T, Cabanero M, Martins-Filho SN, Wang DY, Pasko E, Venkat K, Joseph J, Raghavan V, Zhu CQ, Wang YH, Moghal N, Tsao MS, Navab R. Hao J, et al. Among authors: li q. Neoplasia. 2019 May;21(5):482-493. doi: 10.1016/j.neo.2019.03.009. Epub 2019 Apr 9. Neoplasia. 2019. PMID: 30978569 Free PMC article.
Organoid Cultures as Preclinical Models of Non-Small Cell Lung Cancer.
Shi R, Radulovich N, Ng C, Liu N, Notsuda H, Cabanero M, Martins-Filho SN, Raghavan V, Li Q, Mer AS, Rosen JC, Li M, Wang YH, Tamblyn L, Pham NA, Haibe-Kains B, Liu G, Moghal N, Tsao MS. Shi R, et al. Among authors: li m, li q. Clin Cancer Res. 2020 Mar 1;26(5):1162-1174. doi: 10.1158/1078-0432.CCR-19-1376. Epub 2019 Nov 6. Clin Cancer Res. 2020. PMID: 31694835
EGFR-mutated lung adenocarcinomas from patients who progressed on EGFR-inhibitors show high engraftment rates in xenograft models.
Martins-Filho SN, Weiss J, Pham NA, Li Q, Cabanero M, Fares A, Stewart EL, Shi R, Patel D, Pal P, McConnell J, Bradbury PA, Sacher AG, Leighl NB, Grindlay A, Allison F, Li M, Yasufuku K, Shepherd FA, Moghal N, Tsao MS, Liu G. Martins-Filho SN, et al. Among authors: li m, li q. Lung Cancer. 2020 Jul;145:144-151. doi: 10.1016/j.lungcan.2020.03.022. Epub 2020 May 11. Lung Cancer. 2020. PMID: 32447118
BRAF V600E mutation and MET amplification as resistance pathways of the second-generation anaplastic lymphoma kinase (ALK) inhibitor alectinib in lung cancer.
Shi R, Filho SNM, Li M, Fares A, Weiss J, Pham NA, Ludkovski O, Raghavan V, Li Q, Ravi D, Cabanero M, Moghal N, Leighl NB, Bradbury P, Sacher A, Shepherd FA, Yasufuku K, Tsao MS, Liu G. Shi R, et al. Among authors: li m, li q. Lung Cancer. 2020 Aug;146:78-85. doi: 10.1016/j.lungcan.2020.05.018. Epub 2020 May 21. Lung Cancer. 2020. PMID: 32521388
Predicting Toxicity and Response to Pembrolizumab Through Germline Genomic HLA Class 1 Analysis.
Iafolla MAJ, Yang C, Chandran V, Pintilie M, Li Q, Bedard PL, Hansen A, Lheureux S, Spreafico A, Razak AA, Hakgor S, Giesler A, Pugh TJ, Siu LL. Iafolla MAJ, et al. Among authors: li q. JNCI Cancer Spectr. 2020 Dec 29;5(1):pkaa115. doi: 10.1093/jncics/pkaa115. eCollection 2021 Feb. JNCI Cancer Spectr. 2020. PMID: 33554038 Free PMC article. Clinical Trial.
Lung Cancer Driven by BRAFG469V Mutation Is Targetable by EGFR Kinase Inhibitors.
Huo KG, Notsuda H, Fang Z, Liu NF, Gebregiworgis T, Li Q, Pham NA, Li M, Liu N, Shepherd FA, Marshall CB, Ikura M, Moghal N, Tsao MS. Huo KG, et al. Among authors: li m, li q. J Thorac Oncol. 2022 Feb;17(2):277-288. doi: 10.1016/j.jtho.2021.09.008. Epub 2021 Oct 12. J Thorac Oncol. 2022. PMID: 34648945 Free article.
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