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838 results

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Page 1
In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels.
Rothgangl T, Dennis MK, Lin PJC, Oka R, Witzigmann D, Villiger L, Qi W, Hruzova M, Kissling L, Lenggenhager D, Borrelli C, Egli S, Frey N, Bakker N, Walker JA 2nd, Kadina AP, Victorov DV, Pacesa M, Kreutzer S, Kontarakis Z, Moor A, Jinek M, Weissman D, Stoffel M, van Boxtel R, Holden K, Pardi N, Thöny B, Häberle J, Tam YK, Semple SC, Schwank G. Rothgangl T, et al. Among authors: weissman d. Nat Biotechnol. 2021 Aug;39(8):949-957. doi: 10.1038/s41587-021-00933-4. Epub 2021 May 19. Nat Biotechnol. 2021. PMID: 34012094 Free PMC article.
HPLC purification of in vitro transcribed long RNA.
Weissman D, Pardi N, Muramatsu H, Karikó K. Weissman D, et al. Methods Mol Biol. 2013;969:43-54. doi: 10.1007/978-1-62703-260-5_3. Methods Mol Biol. 2013. PMID: 23296926
Measuring the Adjuvant Activity of RNA Vaccines.
Pardi N, Weissman D. Pardi N, et al. Among authors: weissman d. Methods Mol Biol. 2017;1499:143-153. doi: 10.1007/978-1-4939-6481-9_8. Methods Mol Biol. 2017. PMID: 27987147
Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination.
Pardi N, Hogan MJ, Pelc RS, Muramatsu H, Andersen H, DeMaso CR, Dowd KA, Sutherland LL, Scearce RM, Parks R, Wagner W, Granados A, Greenhouse J, Walker M, Willis E, Yu JS, McGee CE, Sempowski GD, Mui BL, Tam YK, Huang YJ, Vanlandingham D, Holmes VM, Balachandran H, Sahu S, Lifton M, Higgs S, Hensley SE, Madden TD, Hope MJ, Karikó K, Santra S, Graham BS, Lewis MG, Pierson TC, Haynes BF, Weissman D. Pardi N, et al. Among authors: weissman d. Nature. 2017 Mar 9;543(7644):248-251. doi: 10.1038/nature21428. Epub 2017 Feb 2. Nature. 2017. PMID: 28151488 Free PMC article.
Administration of nucleoside-modified mRNA encoding broadly neutralizing antibody protects humanized mice from HIV-1 challenge.
Pardi N, Secreto AJ, Shan X, Debonera F, Glover J, Yi Y, Muramatsu H, Ni H, Mui BL, Tam YK, Shaheen F, Collman RG, Karikó K, Danet-Desnoyers GA, Madden TD, Hope MJ, Weissman D. Pardi N, et al. Among authors: weissman d. Nat Commun. 2017 Mar 2;8:14630. doi: 10.1038/ncomms14630. Nat Commun. 2017. PMID: 28251988 Free PMC article.
mRNA vaccines - a new era in vaccinology.
Pardi N, Hogan MJ, Porter FW, Weissman D. Pardi N, et al. Among authors: weissman d. Nat Rev Drug Discov. 2018 Apr;17(4):261-279. doi: 10.1038/nrd.2017.243. Epub 2018 Jan 12. Nat Rev Drug Discov. 2018. PMID: 29326426 Free PMC article. Review.
838 results