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Design, synthesis, and biological evaluation of new thalidomide-donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation.
Cristancho Ortiz CJ, de Freitas Silva M, Pruccoli L, Fonseca Nadur N, de Azevedo LL, Kümmerle AE, Guedes IA, Dardenne LE, Leomil Coelho LF, Guimarães MJ, da Silva FMR, Castro N, Gontijo VS, Rojas VCT, de Oliveira MK, Vilela FC, Giusti-Paiva A, Barbosa G, Lima LM, Pinheiro GB, Veras LG, Mortari MR, Tarozzi A, Viegas C Jr. Cristancho Ortiz CJ, et al. Among authors: veras lg. RSC Med Chem. 2022 Mar 17;13(5):568-584. doi: 10.1039/d1md00374g. eCollection 2022 May 25. RSC Med Chem. 2022. PMID: 35694691 Free PMC article.