Varshney S - Search Results

1

Disrupting the ghrelin-growth hormone axis limits ghrelin's orexigenic but not glucoregulatory actions.

Gupta D, Patterson AM, Osborne-Lawrence S, Bookout AL, Varshney S, Shankar K, Singh O, Metzger NP, Richard CP, Wyler SC, Elmquist JK, Zigman JM. Gupta D, et al. Among authors: varshney s. Mol Metab. 2021 Nov;53:101258. doi: 10.1016/j.molmet.2021.101258. Epub 2021 May 21. Mol Metab. 2021. PMID: 34023483 Free PMC article.

2

PPP2R5B, a regulatory subunit of PP2A, contributes to adipocyte insulin resistance.

Beg M, Srivastava A, Shankar K, Varshney S, Rajan S, Gupta A, Kumar D, Gaikwad AN. Beg M, et al. Among authors: varshney s. Mol Cell Endocrinol. 2016 Dec 5;437:97-107. doi: 10.1016/j.mce.2016.08.016. Epub 2016 Aug 10. Mol Cell Endocrinol. 2016. PMID: 27521959

3

Curcumin-3,4-Dichloro Phenyl Pyrazole (CDPP) overcomes curcumin's low bioavailability, inhibits adipogenesis and ameliorates dyslipidemia by activating reverse cholesterol transport.

Gupta A, Singh VK, Kumar D, Yadav P, Kumar S, Beg M, Shankar K, Varshney S, Rajan S, Srivastava A, Choudhary R, Balaramnavar VM, Bhatta R, Tadigoppula N, Gaikwad AN. Gupta A, et al. Among authors: varshney s. Metabolism. 2017 Aug;73:109-124. doi: 10.1016/j.metabol.2017.05.005. Epub 2017 May 20. Metabolism. 2017. PMID: 28732567

4

Chronic hyper-leptinemia induces insulin signaling disruption in adipocytes: Implications of NOS2.

Gupta A, Beg M, Kumar D, Shankar K, Varshney S, Rajan S, Srivastava A, Singh K, Sonkar S, Mahdi AA, Dikshit M, Gaikwad AN. Gupta A, et al. Among authors: varshney s. Free Radic Biol Med. 2017 Nov;112:93-108. doi: 10.1016/j.freeradbiomed.2017.07.016. Epub 2017 Jul 22. Free Radic Biol Med. 2017. PMID: 28739528

5

Aegeline inspired synthesis of novel β3-AR agonist improves insulin sensitivity in vitro and in vivo models of insulin resistance.

Rajan S, Satish S, Shankar K, Pandeti S, Varshney S, Srivastava A, Kumar D, Gupta A, Gupta S, Choudhary R, Balaramnavar VM, Narender T, Gaikwad AN. Rajan S, et al. Among authors: varshney s. Metabolism. 2018 Aug;85:1-13. doi: 10.1016/j.metabol.2018.03.001. Epub 2018 Mar 8. Metabolism. 2018. PMID: 29524448

6

Chronic hyperinsulinemia promotes meta-inflammation and extracellular matrix deposition in adipose tissue: Implications of nitric oxide.

Kumar D, Shankar K, Patel S, Gupta A, Varshney S, Gupta S, Rajan S, Srivastava A, Vishwakarma AL, Gaikwad AN. Kumar D, et al. Among authors: varshney s. Mol Cell Endocrinol. 2018 Dec 5;477:15-28. doi: 10.1016/j.mce.2018.05.010. Epub 2018 May 10. Mol Cell Endocrinol. 2018. PMID: 29753026

7

"A LEAP 2 conclusions? Targeting the ghrelin system to treat obesity and diabetes".

Gupta D, Ogden SB, Shankar K, Varshney S, Zigman JM. Gupta D, et al. Among authors: varshney s. Mol Metab. 2021 Apr;46:101128. doi: 10.1016/j.molmet.2020.101128. Epub 2020 Nov 25. Mol Metab. 2021. PMID: 33246141 Free PMC article. Review.

8

LEAP2 deletion in mice enhances ghrelin's actions as an orexigen and growth hormone secretagogue.

Shankar K, Metzger NP, Singh O, Mani BK, Osborne-Lawrence S, Varshney S, Gupta D, Ogden SB, Takemi S, Richard CP, Nandy K, Liu C, Zigman JM. Shankar K, et al. Among authors: varshney s. Mol Metab. 2021 Nov;53:101327. doi: 10.1016/j.molmet.2021.101327. Epub 2021 Aug 21. Mol Metab. 2021. PMID: 34428557 Free PMC article.

9

Ghrelin cell-expressed insulin receptors mediate meal- and obesity-induced declines in plasma ghrelin.

Shankar K, Takemi S, Gupta D, Varshney S, Mani BK, Osborne-Lawrence S, Metzger NP, Richard CP, Berglund ED, Zigman JM. Shankar K, et al. Among authors: varshney s. JCI Insight. 2021 Sep 2;6(18):e146983. doi: 10.1172/jci.insight.146983. JCI Insight. 2021. PMID: 34473648 Free PMC article.

10

Effects of thermoneutrality on food intake, body weight, and body composition in a Prader-Willi syndrome mouse model.

Osborne-Lawrence S, Lawrence C, Metzger NP, Klavon J, Baig HR, Richard C, Varshney S, Gupta D, Singh O, Ogden SB, Shankar K, Paul S, Butler RK, Zigman JM. Osborne-Lawrence S, et al. Among authors: varshney s. Obesity (Silver Spring). 2023 Jun;31(6):1644-1654. doi: 10.1002/oby.23766. Epub 2023 May 10. Obesity (Silver Spring). 2023. PMID: 37161883

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