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Alum:CpG adjuvant enables SARS-CoV-2 RBD-induced protection in aged mice and synergistic activation of human elder type 1 immunity.
Nanishi E, Borriello F, O'Meara TR, McGrath ME, Saito Y, Haupt RE, Seo HS, van Haren SD, Brook B, Chen J, Diray-Arce J, Doss-Gollin S, Leon M, Chew K, Menon M, Song K, Xu AZ, Caradonna TM, Feldman J, Hauser BM, Schmidt AG, Sherman AC, Baden LR, Ernst RK, Dillen C, Weston SM, Johnson RM, Hammond HL, Mayer R, Burke A, Bottazzi ME, Hotez PJ, Strych U, Chang A, Yu J, Barouch DH, Dhe-Paganon S, Zanoni I, Ozonoff A, Frieman MB, Levy O, Dowling DJ. Nanishi E, et al. Among authors: dowling dj. bioRxiv [Preprint]. 2021 May 21:2021.05.20.444848. doi: 10.1101/2021.05.20.444848. bioRxiv. 2021. Update in: Sci Transl Med. 2022 Jan 26;14(629):eabj5305. doi: 10.1126/scitranslmed.abj5305 PMID: 34031655 Free PMC article. Updated. Preprint.
Ontogeny of early life immunity.
Dowling DJ, Levy O. Dowling DJ, et al. Trends Immunol. 2014 Jul;35(7):299-310. doi: 10.1016/j.it.2014.04.007. Epub 2014 May 28. Trends Immunol. 2014. PMID: 24880460 Free PMC article. Review.
TLR7/8 adjuvant overcomes newborn hyporesponsiveness to pneumococcal conjugate vaccine at birth.
Dowling DJ, van Haren SD, Scheid A, Bergelson I, Kim D, Mancuso CJ, Foppen W, Ozonoff A, Fresh L, Theriot TB, Lackner AA, Fichorova RN, Smirnov D, Vasilakos JP, Beaurline JM, Tomai MA, Midkiff CC, Alvarez X, Blanchard JL, Gilbert MH, Aye PP, Levy O. Dowling DJ, et al. JCI Insight. 2017 Mar 23;2(6):e91020. doi: 10.1172/jci.insight.91020. JCI Insight. 2017. PMID: 28352660 Free PMC article.
Identification and Characterization of Stimulator of Interferon Genes As a Robust Adjuvant Target for Early Life Immunization.
Borriello F, Pietrasanta C, Lai JCY, Walsh LM, Sharma P, O'Driscoll DN, Ramirez J, Brightman S, Pugni L, Mosca F, Burkhart DJ, Dowling DJ, Levy O. Borriello F, et al. Among authors: dowling dj. Front Immunol. 2017 Dec 12;8:1772. doi: 10.3389/fimmu.2017.01772. eCollection 2017. Front Immunol. 2017. PMID: 29312305 Free PMC article.
72 results