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A spatial vascular transcriptomic, proteomic, and phosphoproteomic atlas unveils an angiocrine Tie-Wnt signaling axis in the liver.
Inverso D, Shi J, Lee KH, Jakab M, Ben-Moshe S, Kulkarni SR, Schneider M, Wang G, Komeili M, Vélez PA, Riedel M, Spegg C, Ruppert T, Schaeffer-Reiss C, Helm D, Singh I, Boutros M, Chintharlapalli S, Heikenwalder M, Itzkovitz S, Augustin HG. Inverso D, et al. Among authors: chintharlapalli s. Dev Cell. 2021 Jun 7;56(11):1677-1693.e10. doi: 10.1016/j.devcel.2021.05.001. Epub 2021 May 25. Dev Cell. 2021. PMID: 34038707 Free PMC article.
Preclinical validation of a novel metastasis-inhibiting Tie1 function-blocking antibody.
Singhal M, Gengenbacher N, La Porta S, Gehrs S, Shi J, Kamiyama M, Bodenmiller DM, Fischl A, Schieb B, Besemfelder E, Chintharlapalli S, Augustin HG. Singhal M, et al. Among authors: chintharlapalli s. EMBO Mol Med. 2020 Jun 8;12(6):e11164. doi: 10.15252/emmm.201911164. Epub 2020 Apr 17. EMBO Mol Med. 2020. PMID: 32302470 Free PMC article.
Timed Ang2-Targeted Therapy Identifies the Angiopoietin-Tie Pathway as Key Regulator of Fatal Lymphogenous Metastasis.
Gengenbacher N, Singhal M, Mogler C, Hai L, Milde L, Pari AAA, Besemfelder E, Fricke C, Baumann D, Gehrs S, Utikal J, Felcht M, Hu J, Schlesner M, Offringa R, Chintharlapalli SR, Augustin HG. Gengenbacher N, et al. Among authors: chintharlapalli sr. Cancer Discov. 2021 Feb;11(2):424-445. doi: 10.1158/2159-8290.CD-20-0122. Epub 2020 Oct 26. Cancer Discov. 2021. PMID: 33106316
Inhibition of Sphingosine Phosphate Receptor 1 Signaling Enhances the Efficacy of VEGF Receptor Inhibition.
Fischl AS, Wang X, Falcon BL, Almonte-Baldonado R, Bodenmiller D, Evans G, Stewart J, Wilson T, Hipskind P, Manro J, Uhlik MT, Chintharlapalli S, Gerald D, Alsop DC, Benjamin LE, Bhatt RS. Fischl AS, et al. Among authors: chintharlapalli s. Mol Cancer Ther. 2019 Apr;18(4):856-867. doi: 10.1158/1535-7163.MCT-18-0548. Epub 2019 Feb 20. Mol Cancer Ther. 2019. PMID: 30787172 Free PMC article.
Stromal-Based Signatures for the Classification of Gastric Cancer.
Uhlik MT, Liu J, Falcon BL, Iyer S, Stewart J, Celikkaya H, O'Mahony M, Sevinsky C, Lowes C, Douglass L, Jeffries C, Bodenmiller D, Chintharlapalli S, Fischl A, Gerald D, Xue Q, Lee JY, Santamaria-Pang A, Al-Kofahi Y, Sui Y, Desai K, Doman T, Aggarwal A, Carter JH, Pytowski B, Jaminet SC, Ginty F, Nasir A, Nagy JA, Dvorak HF, Benjamin LE. Uhlik MT, et al. Among authors: chintharlapalli s. Cancer Res. 2016 May 1;76(9):2573-86. doi: 10.1158/0008-5472.CAN-16-0022. Cancer Res. 2016. PMID: 27197264
Tasisulam sodium, an antitumor agent that inhibits mitotic progression and induces vascular normalization.
Meier T, Uhlik M, Chintharlapalli S, Dowless M, Van Horn R, Stewart J, Blosser W, Cook J, Young D, Ye X, Evans G, Credille K, Ballard D, Huber L, Capen A, Chedid M, Ilaria R Jr, Smith MC, Stancato L. Meier T, et al. Among authors: chintharlapalli s. Mol Cancer Ther. 2011 Nov;10(11):2168-78. doi: 10.1158/1535-7163.MCT-11-0323. Epub 2011 Sep 8. Mol Cancer Ther. 2011. PMID: 21903607
Angiopoietin-2 Blockade Promotes Survival of Corneal Transplants.
Zhang L, Li G, Sessa R, Kang GJ, Shi M, Ge S, Gong AJ, Wen Y, Chintharlapalli S, Chen L. Zhang L, et al. Among authors: chintharlapalli s. Invest Ophthalmol Vis Sci. 2017 Jan 1;58(1):79-86. doi: 10.1167/iovs.16-20485. Invest Ophthalmol Vis Sci. 2017. PMID: 28061513 Free PMC article.
54 results