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MARK4 controls ischaemic heart failure through microtubule detyrosination.
Yu X, Chen X, Amrute-Nayak M, Allgeyer E, Zhao A, Chenoweth H, Clement M, Harrison J, Doreth C, Sirinakis G, Krieg T, Zhou H, Huang H, Tokuraku K, Johnston DS, Mallat Z, Li X. Yu X, et al. Among authors: doreth c. Nature. 2021 Jun;594(7864):560-565. doi: 10.1038/s41586-021-03573-5. Epub 2021 May 26. Nature. 2021. PMID: 34040253 Free PMC article.
PLK1 inhibition dampens NLRP3 inflammasome-elicited response in inflammatory disease models.
Baldrighi M, Doreth C, Li Y, Zhao X, Warner E, Chenoweth H, Kishore K, Umrania Y, Minde DP, Thome S, Yu X, Lu Y, Knapton A, Harrison J, Clarke M, Latz E, de Cárcer G, Malumbres M, Ryffel B, Bryant C, Liu J, Lilley KS, Mallat Z, Li X. Baldrighi M, et al. Among authors: doreth c. J Clin Invest. 2023 Nov 1;133(21):e162129. doi: 10.1172/JCI162129. J Clin Invest. 2023. PMID: 37698938 Free PMC article.
DEL-1 promotes macrophage efferocytosis and clearance of inflammation.
Kourtzelis I, Li X, Mitroulis I, Grosser D, Kajikawa T, Wang B, Grzybek M, von Renesse J, Czogalla A, Troullinaki M, Ferreira A, Doreth C, Ruppova K, Chen LS, Hosur K, Lim JH, Chung KJ, Grossklaus S, Tausche AK, Joosten LAB, Moutsopoulos NM, Wielockx B, Castrillo A, Korostoff JM, Coskun Ü, Hajishengallis G, Chavakis T. Kourtzelis I, et al. Among authors: doreth c. Nat Immunol. 2019 Jan;20(1):40-49. doi: 10.1038/s41590-018-0249-1. Epub 2018 Nov 19. Nat Immunol. 2019. PMID: 30455459 Free PMC article.