Nucleotide Excision Repair Lesion-Recognition Protein Rad4 Captures a Pre-Flipped Partner Base in a Benzo[a]pyrene-Derived DNA Lesion: How Structure Impacts the Binding Pathway.
Mu H, Geacintov NE, Min JH, Zhang Y, Broyde S.
Mu H, et al.
Chem Res Toxicol. 2017 Jun 19;30(6):1344-1354. doi: 10.1021/acs.chemrestox.7b00074. Epub 2017 May 15.
Chem Res Toxicol. 2017.
PMID: 28460163
Free PMC article.
This binding path differs significantly from the one deduced for the small cis-syn cyclobutane pyrimidine dimer lesion opposite mismatched thymines [ Mu , H. , ( 2015 ) Biochemistry , 54 ( 34 ), 5263 - 7 ]. The possibility of multiple paths that lead to productive b …
This binding path differs significantly from the one deduced for the small cis-syn cyclobutane pyrimidine dimer lesion opposite mismatched t …