Martinez-Fleites C - Search Results

1

The role of small molecules in cell and gene therapy.

Brayshaw LL, Martinez-Fleites C, Athanasopoulos T, Southgate T, Jespers L, Herring C. Brayshaw LL, et al. Among authors: martinez fleites c. RSC Med Chem. 2020 Dec 24;12(3):330-352. doi: 10.1039/d0md00221f. eCollection 2021 Mar 1. RSC Med Chem. 2020. PMID: 34046619 Free PMC article. Review.

2

Structural insights into the disruption of TNF-TNFR1 signalling by small molecules stabilising a distorted TNF.

McMillan D, Martinez-Fleites C, Porter J, Fox D 3rd, Davis R, Mori P, Ceska T, Carrington B, Lawson A, Bourne T, O'Connell J. McMillan D, et al. Among authors: martinez fleites c. Nat Commun. 2021 Jan 25;12(1):582. doi: 10.1038/s41467-020-20828-3. Nat Commun. 2021. PMID: 33495441 Free PMC article.

3

Structure of a flavonoid glucosyltransferase reveals the basis for plant natural product modification.

Offen W, Martinez-Fleites C, Yang M, Kiat-Lim E, Davis BG, Tarling CA, Ford CM, Bowles DJ, Davies GJ. Offen W, et al. EMBO J. 2006 Mar 22;25(6):1396-405. doi: 10.1038/sj.emboj.7600970. Epub 2006 Feb 16. EMBO J. 2006. PMID: 16482224 Free PMC article.

4

Structural dissection and high-throughput screening of mannosylglycerate synthase.

Flint J, Taylor E, Yang M, Bolam DN, Tailford LE, Martinez-Fleites C, Dodson EJ, Davis BG, Gilbert HJ, Davies GJ. Flint J, et al. Nat Struct Mol Biol. 2005 Jul;12(7):608-14. doi: 10.1038/nsmb950. Epub 2005 Jun 12. Nat Struct Mol Biol. 2005. PMID: 15951819

5

The crystal structure of two macrolide glycosyltransferases provides a blueprint for host cell antibiotic immunity.

Bolam DN, Roberts S, Proctor MR, Turkenburg JP, Dodson EJ, Martinez-Fleites C, Yang M, Davis BG, Davies GJ, Gilbert HJ. Bolam DN, et al. Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5336-41. doi: 10.1073/pnas.0607897104. Epub 2007 Mar 21. Proc Natl Acad Sci U S A. 2007. PMID: 17376874 Free PMC article.

6

Structure of an O-GlcNAc transferase homolog provides insight into intracellular glycosylation.

Martinez-Fleites C, Macauley MS, He Y, Shen DL, Vocadlo DJ, Davies GJ. Martinez-Fleites C, et al. Nat Struct Mol Biol. 2008 Jul;15(7):764-5. doi: 10.1038/nsmb.1443. Epub 2008 Jun 8. Nat Struct Mol Biol. 2008. PMID: 18536723

7

Crystal structure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558.

Ruane KM, Davies GJ, Martinez-Fleites C. Ruane KM, et al. Proteins. 2008 Nov 15;73(3):784-7. doi: 10.1002/prot.22171. Proteins. 2008. PMID: 18712829 No abstract available.

8

Structural analyses of enzymes involved in the O-GlcNAc modification.

Martinez-Fleites C, He Y, Davies GJ. Martinez-Fleites C, et al. Biochim Biophys Acta. 2010 Feb;1800(2):122-33. doi: 10.1016/j.bbagen.2009.07.019. Epub 2009 Jul 30. Biochim Biophys Acta. 2010. PMID: 19647042 Review.

9

Mechanistic insight into enzymatic glycosyl transfer with retention of configuration through analysis of glycomimetic inhibitors.

Errey JC, Lee SS, Gibson RP, Martinez Fleites C, Barry CS, Jung PM, O'Sullivan AC, Davis BG, Davies GJ. Errey JC, et al. Among authors: martinez fleites c. Angew Chem Int Ed Engl. 2010 Feb 8;49(7):1234-7. doi: 10.1002/anie.200905096. Angew Chem Int Ed Engl. 2010. PMID: 20077550 No abstract available.

10

GlaxoSmithKline Award Lecture. The O-GlcNAc modification: three-dimensional structure, enzymology and the development of selective inhibitors to probe disease.

Davies GJ, Martinez-Fleites C. Davies GJ, et al. Among authors: martinez fleites c. Biochem Soc Trans. 2010 Oct;38(5):1179-88. doi: 10.1042/BST0381179. Biochem Soc Trans. 2010. PMID: 20863281 Review.

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