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Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells.
Shmuel-Galia L, Humphries F, Lei X, Ceglia S, Wilson R, Jiang Z, Ketelut-Carneiro N, Foley SE, Pechhold S, Houghton J, Muneeruddin K, Shaffer SA, McCormick BA, Reboldi A, Ward D, Marshak-Rothstein A, Fitzgerald KA. Shmuel-Galia L, et al. Among authors: lei x. Immunity. 2021 Jun 8;54(6):1137-1153.e8. doi: 10.1016/j.immuni.2021.05.008. Epub 2021 May 28. Immunity. 2021. PMID: 34051146 Free PMC article.
The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2.
Vierbuchen T, Agarwal S, Johnson JL, Galia L, Lei X, Stein K, Olagnier D, Gaede KI, Herzmann C, Holm CK, Heine H, Pai A, O'Hara Hall A, Hoebe K, Fitzgerald KA. Vierbuchen T, et al. Among authors: lei x. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2213715120. doi: 10.1073/pnas.2213715120. Epub 2022 Dec 28. Proc Natl Acad Sci U S A. 2023. PMID: 36577072 Free PMC article.
Cellular nucleic acid-binding protein restricts SARS-CoV-2 by regulating interferon and disrupting RNA-protein condensates.
Chen Y, Lei X, Jiang Z, Humphries F, Parsi KM, Mustone NJ, Ramos I, Mutetwa T, Fernandez-Sesma A, Maehr R, Caffrey DR, Fitzgerald KA. Chen Y, et al. Among authors: lei x. Proc Natl Acad Sci U S A. 2023 Nov 21;120(47):e2308355120. doi: 10.1073/pnas.2308355120. Epub 2023 Nov 14. Proc Natl Acad Sci U S A. 2023. PMID: 37963251 Free PMC article.
The RNA helicase Dhx15 mediates Wnt-induced antimicrobial protein expression in Paneth cells.
Wang Y, He K, Sheng B, Lei X, Tao W, Zhu X, Wei Z, Fu R, Wang A, Bai S, Zhang Z, Hong N, Ye C, Tian Y, Wang J, Li M, Zhang K, Li L, Yang H, Li HB, Flavell RA, Zhu S. Wang Y, et al. Among authors: lei x. Proc Natl Acad Sci U S A. 2021 Jan 26;118(4):e2017432118. doi: 10.1073/pnas.2017432118. Proc Natl Acad Sci U S A. 2021. PMID: 33483420 Free PMC article.
Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells.
Zhu S, Ding S, Wang P, Wei Z, Pan W, Palm NW, Yang Y, Yu H, Li HB, Wang G, Lei X, de Zoete MR, Zhao J, Zheng Y, Chen H, Zhao Y, Jurado KA, Feng N, Shan L, Kluger Y, Lu J, Abraham C, Fikrig E, Greenberg HB, Flavell RA. Zhu S, et al. Among authors: lei x. Nature. 2017 Jun 29;546(7660):667-670. doi: 10.1038/nature22967. Epub 2017 Jun 21. Nature. 2017. PMID: 28636595 Free PMC article.
The effect of a new thinking guidance of OPACCUS for shock on the 30-day mortality: A multicenter, prospective, observational, cohort study.
Li Y, Zou T, Zeng X, Qin Y, Zhou R, Cao L, Hu J, Lei X, Dong Q, Qin Y, Zhang G, Kang Y, Wang B, Zhang Z, Wang X, Chao Y, Yin W; Critical Care Ultrasound Study Group (CCUSG); Committee on Critical Care Ultrasound and Hemodynamics (CCUSH, SCIMEA). Li Y, et al. Among authors: lei x. Eur J Intern Med. 2024 Dec 26:S0953-6205(24)00500-4. doi: 10.1016/j.ejim.2024.12.007. Online ahead of print. Eur J Intern Med. 2024. PMID: 39730239
4,908 results