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Ligand conjugate SAR and enhanced delivery in NHP.
Holland RJ, Lam K, Ye X, Martin AD, Wood MC, Palmer L, Fraser D, McClintock K, Majeski S, Jarosz A, Lee ACH, Thi EP, Judge A, Heyes J. Holland RJ, et al. Among authors: martin ad. Mol Ther. 2021 Oct 6;29(10):2910-2919. doi: 10.1016/j.ymthe.2021.06.002. Epub 2021 Jun 4. Mol Ther. 2021. PMID: 34091052 Free PMC article.
Preclinical development of SGN-CD47M: Protease-activated antibody technology enables selective tumor targeting of the innate immune checkpoint receptor CD47.
Levengood MR, Carosino CM, Zhang X, Lucas S, Ortiz DJ, Westendorf L, Chin AP, Martin AD, Wong A, Hengel SM, Sun H, Zeng W, Yumul R, Dominguez MM, Chen Y, Zheng JH, Karlsson CAB, Trang VH, Senter PD, Gardai SJ. Levengood MR, et al. Among authors: martin ad. Mol Cancer Ther. 2024 Oct 28. doi: 10.1158/1535-7163.MCT-24-0371. Online ahead of print. Mol Cancer Ther. 2024. PMID: 39463068
282 results