Olsen SK - Search Results

1

PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis.

Yin S, Liu L, Brobbey C, Palanisamy V, Ball LE, Olsen SK, Ostrowski MC, Gan W. Yin S, et al. Among authors: olsen sk. Nat Commun. 2021 Jun 8;12(1):3444. doi: 10.1038/s41467-021-23833-2. Nat Commun. 2021. PMID: 34103528 Free PMC article.

2

Structural insights into the mechanism and E2 specificity of the RBR E3 ubiquitin ligase HHARI.

Yuan L, Lv Z, Atkison JH, Olsen SK. Yuan L, et al. Among authors: olsen sk. Nat Commun. 2017 Aug 8;8(1):211. doi: 10.1038/s41467-017-00272-6. Nat Commun. 2017. PMID: 28790309 Free PMC article.

3

Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme.

Lv Z, Yuan L, Atkison JH, Williams KM, Vega R, Sessions EH, Divlianska DB, Davies C, Chen Y, Olsen SK. Lv Z, et al. Among authors: olsen sk. Nat Commun. 2018 Dec 4;9(1):5145. doi: 10.1038/s41467-018-07015-1. Nat Commun. 2018. PMID: 30514846 Free PMC article.

4

Structural insights into E1 recognition and the ubiquitin-conjugating activity of the E2 enzyme Cdc34.

Williams KM, Qie S, Atkison JH, Salazar-Arango S, Alan Diehl J, Olsen SK. Williams KM, et al. Among authors: olsen sk. Nat Commun. 2019 Jul 24;10(1):3296. doi: 10.1038/s41467-019-11061-8. Nat Commun. 2019. PMID: 31341161 Free PMC article.

5

Crystal structures of an E1-E2-ubiquitin thioester mimetic reveal molecular mechanisms of transthioesterification.

Yuan L, Lv Z, Adams MJ, Olsen SK. Yuan L, et al. Among authors: olsen sk. Nat Commun. 2021 Apr 22;12(1):2370. doi: 10.1038/s41467-021-22598-y. Nat Commun. 2021. PMID: 33888705 Free PMC article.

6

Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity.

Lv D, Pal P, Liu X, Jia Y, Thummuri D, Zhang P, Hu W, Pei J, Zhang Q, Zhou S, Khan S, Zhang X, Hua N, Yang Q, Arango S, Zhang W, Nayak D, Olsen SK, Weintraub ST, Hromas R, Konopleva M, Yuan Y, Zheng G, Zhou D. Lv D, et al. Among authors: olsen sk. Nat Commun. 2021 Nov 25;12(1):6896. doi: 10.1038/s41467-021-27210-x. Nat Commun. 2021. PMID: 34824248 Free PMC article.

7

Crystal structures reveal catalytic and regulatory mechanisms of the dual-specificity ubiquitin/FAT10 E1 enzyme Uba6.

Yuan L, Gao F, Lv Z, Nayak D, Nayak A, Santos Bury PD, Cano KE, Jia L, Oleinik N, Atilgan FC, Ogretmen B, Williams KM, Davies C, El Oualid F, Wasmuth EV, Olsen SK. Yuan L, et al. Among authors: olsen sk. Nat Commun. 2022 Aug 19;13(1):4880. doi: 10.1038/s41467-022-32613-5. Nat Commun. 2022. PMID: 35986001 Free PMC article.

8

Cryo-EM structures of Uba7 reveal the molecular basis for ISG15 activation and E1-E2 thioester transfer.

Afsar M, Liu G, Jia L, Ruben EA, Nayak D, Sayyad Z, Bury PDS, Cano KE, Nayak A, Zhao XR, Shukla A, Sung P, Wasmuth EV, Gack MU, Olsen SK. Afsar M, et al. Among authors: olsen sk. Nat Commun. 2023 Aug 8;14(1):4786. doi: 10.1038/s41467-023-39780-z. Nat Commun. 2023. PMID: 37553340 Free PMC article.

9

Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL.

Nayak D, Lv D, Yuan Y, Zhang P, Hu W, Nayak A, Ruben EA, Lv Z, Sung P, Hromas R, Zheng G, Zhou D, Olsen SK. Nayak D, et al. Among authors: olsen sk. Nat Commun. 2024 Mar 29;15(1):2743. doi: 10.1038/s41467-024-46922-4. Nat Commun. 2024. PMID: 38548768 Free PMC article.

10

Structural insights into BCDX2 complex function in homologous recombination.

Rawal Y, Jia L, Meir A, Zhou S, Kaur H, Ruben EA, Kwon Y, Bernstein KA, Jasin M, Taylor AB, Burma S, Hromas R, Mazin AV, Zhao W, Zhou D, Wasmuth EV, Greene EC, Sung P, Olsen SK. Rawal Y, et al. Among authors: olsen sk. Nature. 2023 Jul;619(7970):640-649. doi: 10.1038/s41586-023-06219-w. Epub 2023 Jun 21. Nature. 2023. PMID: 37344589 Free PMC article.

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