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PELP1/SRC-3-dependent regulation of metabolic PFKFB kinases drives therapy resistant ER+ breast cancer.
Truong TH, Benner EA, Hagen KM, Temiz NA, Kerkvliet CP, Wang Y, Cortes-Sanchez E, Yang CH, Trousdell MC, Pengo T, Guillen KP, Welm BE, Dos Santos CO, Telang S, Lange CA, Ostrander JH. Truong TH, et al. Among authors: kerkvliet cp. Oncogene. 2021 Jun;40(25):4384-4397. doi: 10.1038/s41388-021-01871-w. Epub 2021 Jun 8. Oncogene. 2021. PMID: 34103681 Free PMC article.
Breast Tumor Kinase (Brk/PTK6) Mediates Advanced Cancer Phenotypes via SH2-Domain Dependent Activation of RhoA and Aryl Hydrocarbon Receptor (AhR) Signaling.
Dwyer AR, Kerkvliet CP, Krutilina RI, Playa HC, Parke DN, Thomas WA, Smeester BA, Moriarity BS, Seagroves TN, Lange CA. Dwyer AR, et al. Among authors: kerkvliet cp. Mol Cancer Res. 2021 Feb;19(2):329-345. doi: 10.1158/1541-7786.MCR-20-0295. Epub 2020 Nov 10. Mol Cancer Res. 2021. PMID: 33172975 Free PMC article.