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11βHSD1 Inhibition with AZD4017 Improves Lipid Profiles and Lean Muscle Mass in Idiopathic Intracranial Hypertension.
Hardy RS, Botfield H, Markey K, Mitchell JL, Alimajstorovic Z, Westgate CSJ, Sagmeister M, Fairclough RJ, Ottridge RS, Yiangou A, Storbeck KH, Taylor AE, Gilligan LC, Arlt W, Stewart PM, Tomlinson JW, Mollan SP, Lavery GG, Sinclair AJ. Hardy RS, et al. Among authors: lavery gg. J Clin Endocrinol Metab. 2021 Jan 1;106(1):174-187. doi: 10.1210/clinem/dgaa766. J Clin Endocrinol Metab. 2021. PMID: 33098644 Free PMC article. Clinical Trial.
11β-Hydroxysteroid Dehydrogenase Type 1 within Osteoclasts Mediates the Bone Protective Properties of Therapeutic Corticosteroids in Chronic Inflammation.
Fenton CG, Crastin A, Martin CS, Suresh S, Montagna I, Hussain B, Naylor AJ, Jones SW, Hansen MS, Gorvin CM, Price M, Filer A, Cooper MS, Lavery GG, Raza K, Hardy RS. Fenton CG, et al. Among authors: lavery gg. Int J Mol Sci. 2022 Jun 30;23(13):7334. doi: 10.3390/ijms23137334. Int J Mol Sci. 2022. PMID: 35806338 Free PMC article.
11β-HSD1 determines the extent of muscle atrophy in a model of acute exacerbation of COPD.
Webster JM, Waaijenberg K, van de Worp WRPH, Kelders MCJM, Lambrichts S, Martin C, Verhaegen F, Van der Heyden B, Smith C, Lavery GG, Schols AMWJ, Hardy RS, Langen RCJ. Webster JM, et al. Among authors: lavery gg. Am J Physiol Lung Cell Mol Physiol. 2023 Apr 1;324(4):L400-L412. doi: 10.1152/ajplung.00009.2022. Epub 2023 Feb 21. Am J Physiol Lung Cell Mol Physiol. 2023. PMID: 36807882 Free PMC article.
162 results