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Page 1
Integrated transcriptomic analysis of human tuberculosis granulomas and a biomimetic model identifies therapeutic targets.
Reichmann MT, Tezera LB, Vallejo AF, Vukmirovic M, Xiao R, Reynolds J, Jogai S, Wilson S, Marshall B, Jones MG, Leslie A, D'Armiento JM, Kaminski N, Polak ME, Elkington P. Reichmann MT, et al. Among authors: jones mg. J Clin Invest. 2021 Aug 2;131(15):e148136. doi: 10.1172/JCI148136. J Clin Invest. 2021. PMID: 34128839 Free PMC article.
Three-dimensional characterization of fibroblast foci in idiopathic pulmonary fibrosis.
Jones MG, Fabre A, Schneider P, Cinetto F, Sgalla G, Mavrogordato M, Jogai S, Alzetani A, Marshall BG, O'Reilly KM, Warner JA, Lackie PM, Davies DE, Hansell DM, Nicholson AG, Sinclair I, Brown KK, Richeldi L. Jones MG, et al. JCI Insight. 2016 Apr 21;1(5):e86375. doi: 10.1172/jci.insight.86375. JCI Insight. 2016. PMID: 27275013 Free PMC article.
The safety of new drug treatments for idiopathic pulmonary fibrosis.
Fletcher S, Jones MG, Spinks K, Sgalla G, Marshall BG, Limbrey R, Richeldi L. Fletcher S, et al. Among authors: jones mg. Expert Opin Drug Saf. 2016 Nov;15(11):1483-1489. doi: 10.1080/14740338.2016.1218470. Epub 2016 Aug 17. Expert Opin Drug Saf. 2016. PMID: 27532218 Review.
Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis.
Jones MG, Andriotis OG, Roberts JJ, Lunn K, Tear VJ, Cao L, Ask K, Smart DE, Bonfanti A, Johnson P, Alzetani A, Conforti F, Doherty R, Lai CY, Johnson B, Bourdakos KN, Fletcher SV, Marshall BG, Jogai S, Brereton CJ, Chee SJ, Ottensmeier CH, Sime P, Gauldie J, Kolb M, Mahajan S, Fabre A, Bhaskar A, Jarolimek W, Richeldi L, O'Reilly KM, Monk PD, Thurner PJ, Davies DE. Jones MG, et al. Elife. 2018 Jul 3;7:e36354. doi: 10.7554/eLife.36354. Elife. 2018. PMID: 29966587 Free PMC article.
Bidirectional epithelial-mesenchymal crosstalk provides self-sustaining profibrotic signals in pulmonary fibrosis.
Yao L, Zhou Y, Li J, Wickens L, Conforti F, Rattu A, Ibrahim FM, Alzetani A, Marshall BG, Fletcher SV, Hancock D, Wallis T, Downward J, Ewing RM, Richeldi L, Skipp P, Davies DE, Jones MG, Wang Y. Yao L, et al. Among authors: jones mg. J Biol Chem. 2021 Sep;297(3):101096. doi: 10.1016/j.jbc.2021.101096. Epub 2021 Aug 18. J Biol Chem. 2021. PMID: 34418430 Free PMC article.
Pseudohypoxic HIF pathway activation dysregulates collagen structure-function in human lung fibrosis.
Brereton CJ, Yao L, Davies ER, Zhou Y, Vukmirovic M, Bell JA, Wang S, Ridley RA, Dean LSN, Andriotis OG, Conforti F, Brewitz L, Mohammed S, Wallis T, Tavassoli A, Ewing RM, Alzetani A, Marshall BG, Fletcher SV, Thurner PJ, Fabre A, Kaminski N, Richeldi L, Bhaskar A, Schofield CJ, Loxham M, Davies DE, Wang Y, Jones MG. Brereton CJ, et al. Among authors: jones mg. Elife. 2022 Feb 21;11:e69348. doi: 10.7554/eLife.69348. Elife. 2022. PMID: 35188460 Free PMC article.
Towards an artificial human lung: modelling organ-like complexity to aid mechanistic understanding.
Humbert MV, Spalluto CM, Bell J, Blume C, Conforti F, Davies ER, Dean LSN, Elkington P, Haitchi HM, Jackson C, Jones MG, Loxham M, Lucas JS, Morgan H, Polak M, Staples KJ, Swindle EJ, Tezera L, Watson A, Wilkinson TMA. Humbert MV, et al. Among authors: jones mg. Eur Respir J. 2022 Dec 8;60(6):2200455. doi: 10.1183/13993003.00455-2022. Print 2022 Dec. Eur Respir J. 2022. PMID: 35777774 Free article. Review.
Spatially resolved deconvolution of the fibrotic niche in lung fibrosis.
Eyres M, Bell JA, Davies ER, Fabre A, Alzetani A, Jogai S, Marshall BG, Johnston DA, Xu Z, Fletcher SV, Wang Y, Marshall G, Davies DE, Offer E, Jones MG. Eyres M, et al. Among authors: jones mg. Cell Rep. 2022 Aug 16;40(7):111230. doi: 10.1016/j.celrep.2022.111230. Cell Rep. 2022. PMID: 35977489 Free PMC article.
329 results