Suda A - Search Results

1

In vivo-in vitro correlation of antitumor activity of heat shock protein 90 (HSP90) inhibitors with a pharmacokinetics/pharmacodynamics analysis using NCI-N87 xenograft mice.

Ohminato N, Nagayasu M, Ozeki K, Saitoh R, Ono N, Shibahara N, Suda A, Yoshinari K. Ohminato N, et al. Among authors: suda a. Xenobiotica. 2021 Sep;51(9):968-976. doi: 10.1080/00498254.2021.1942588. Epub 2021 Aug 19. Xenobiotica. 2021. PMID: 34134599

2

Preclinical antitumor activity of the novel heat shock protein 90 inhibitor CH5164840 against human epidermal growth factor receptor 2 (HER2)-overexpressing cancers.

Ono N, Yamazaki T, Nakanishi Y, Fujii T, Sakata K, Tachibana Y, Suda A, Hada K, Miura T, Sato S, Saitoh R, Nakano K, Tsukuda T, Mio T, Ishii N, Kondoh O, Aoki Y. Ono N, et al. Among authors: suda a. Cancer Sci. 2012 Feb;103(2):342-9. doi: 10.1111/j.1349-7006.2011.02144.x. Epub 2011 Dec 13. Cancer Sci. 2012. PMID: 22050138 Free article.

3

Assessing the impact of HER2 status on the antitumor activity of an HSP90 inhibitor in human tumor xenograft mice using pharmacokinetic-pharmacodynamic modeling.

Saitoh R, Nagayasu M, Shibahara N, Ono N, Suda A, Kato M, Ishigai M. Saitoh R, et al. Among authors: suda a. Drug Metab Pharmacokinet. 2014;29(2):185-91. doi: 10.2133/dmpk.dmpk-13-rg-066. Epub 2013 Oct 15. Drug Metab Pharmacokinet. 2014. PMID: 24126359 Free article.

4

Lead generation of heat shock protein 90 inhibitors by a combination of fragment-based approach, virtual screening, and structure-based drug design.

Miura T, Fukami TA, Hasegawa K, Ono N, Suda A, Shindo H, Yoon DO, Kim SJ, Na YJ, Aoki Y, Shimma N, Tsukuda T, Shiratori Y. Miura T, et al. Among authors: suda a. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5778-83. doi: 10.1016/j.bmcl.2011.08.001. Epub 2011 Aug 6. Bioorg Med Chem Lett. 2011. PMID: 21875802

5

Design and synthesis of novel macrocyclic 2-amino-6-arylpyrimidine Hsp90 inhibitors.

Suda A, Koyano H, Hayase T, Hada K, Kawasaki K, Komiyama S, Hasegawa K, Fukami TA, Sato S, Miura T, Ono N, Yamazaki T, Saitoh R, Shimma N, Shiratori Y, Tsukuda T. Suda A, et al. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1136-41. doi: 10.1016/j.bmcl.2011.11.100. Epub 2011 Dec 1. Bioorg Med Chem Lett. 2012. PMID: 22192591

6

Enhanced antitumor activity of erlotinib in combination with the Hsp90 inhibitor CH5164840 against non-small-cell lung cancer.

Ono N, Yamazaki T, Tsukaguchi T, Fujii T, Sakata K, Suda A, Tsukuda T, Mio T, Ishii N, Kondoh O, Aoki Y. Ono N, et al. Among authors: suda a. Cancer Sci. 2013 Oct;104(10):1346-52. doi: 10.1111/cas.12237. Epub 2013 Aug 20. Cancer Sci. 2013. PMID: 23863134 Free PMC article.

7

Design and synthesis of 2-amino-6-(1H,3H-benzo[de]isochromen-6-yl)-1,3,5-triazines as novel Hsp90 inhibitors.

Suda A, Kawasaki K, Komiyama S, Isshiki Y, Yoon DO, Kim SJ, Na YJ, Hasegawa K, Fukami TA, Sato S, Miura T, Ono N, Yamazaki T, Saitoh R, Shimma N, Shiratori Y, Tsukuda T. Suda A, et al. Bioorg Med Chem. 2014 Jan 15;22(2):892-905. doi: 10.1016/j.bmc.2013.11.036. Epub 2013 Nov 25. Bioorg Med Chem. 2014. PMID: 24369839

8

Retinal toxicity induced by small-molecule Hsp90 inhibitors in beagle dogs.

Kanamaru C, Yamada Y, Hayashi S, Matsushita T, Suda A, Nagayasu M, Kimura K, Chiba S. Kanamaru C, et al. Among authors: suda a. J Toxicol Sci. 2014 Feb;39(1):59-69. doi: 10.2131/jts.39.59. J Toxicol Sci. 2014. PMID: 24418710 Free article.

9

Angiogenesis inhibitors identified by cell-based high-throughput screening: synthesis, structure-activity relationships and biological evaluation of 3-[(E)-styryl]benzamides that specifically inhibit endothelial cell proliferation.

Hada K, Suda A, Asoh K, Tsukuda T, Hasegawa M, Sato Y, Ogawa K, Kuramoto S, Aoki Y, Shimma N, Ishikawa T, Koyano H. Hada K, et al. Among authors: suda a. Bioorg Med Chem. 2012 Feb 15;20(4):1442-60. doi: 10.1016/j.bmc.2011.12.058. Epub 2012 Jan 5. Bioorg Med Chem. 2012. PMID: 22269278

10

Distribution of lectin binding in spermatogonia of Syrian hamsters in gonadally active and inactive states.

Suda A, Hashimoto O, Ogawa K, Kurohmaru M, Hayashi Y. Suda A, et al. J Vet Med Sci. 1998 Feb;60(2):189-95. doi: 10.1292/jvms.60.189. J Vet Med Sci. 1998. PMID: 9524942 Free article.

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