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Page 1
The ingenol-based protein kinase C agonist GSK445A is a potent inducer of HIV and SIV RNA transcription.
Okoye AA, Fromentin R, Takata H, Brehm JH, Fukazawa Y, Randall B, Pardons M, Tai V, Tang J, Smedley J, Axthelm M, Lifson JD, Picker LJ, Favre D, Trautmann L, Chomont N. Okoye AA, et al. Among authors: pardons m. PLoS Pathog. 2022 Jan 18;18(1):e1010245. doi: 10.1371/journal.ppat.1010245. eCollection 2022 Jan. PLoS Pathog. 2022. PMID: 35041707 Free PMC article.
First-in-human immunoPET imaging of HIV-1 infection using 89Zr-labeled VRC01 broadly neutralizing antibody.
Beckford-Vera DR, Flavell RR, Seo Y, Martinez-Ortiz E, Aslam M, Thanh C, Fehrman E, Pardons M, Kumar S, Deitchman AN, Ravanfar V, Schulte B, Wu IK, Pan T, Reeves JD, Nixon CC, Iyer NS, Torres L, Munter SE, Hyunh T, Petropoulos CJ, Hoh R, Franc BL, Gama L, Koup RA, Mascola JR, Chomont N, Deeks SG, VanBrocklin HF, Henrich TJ. Beckford-Vera DR, et al. Among authors: pardons m. Nat Commun. 2022 Mar 9;13(1):1219. doi: 10.1038/s41467-022-28727-5. Nat Commun. 2022. PMID: 35264559 Free PMC article.
HIV rapidly targets a diverse pool of CD4+ T cells to establish productive and latent infections.
Gantner P, Buranapraditkun S, Pagliuzza A, Dufour C, Pardons M, Mitchell JL, Kroon E, Sacdalan C, Tulmethakaan N, Pinyakorn S, Robb ML, Phanuphak N, Ananworanich J, Hsu D, Vasan S, Trautmann L, Fromentin R, Chomont N. Gantner P, et al. Among authors: pardons m. Immunity. 2023 Mar 14;56(3):653-668.e5. doi: 10.1016/j.immuni.2023.01.030. Epub 2023 Feb 17. Immunity. 2023. PMID: 36804957 Free PMC article.
Sequential treatment with 5-aza-2'-deoxycytidine and deacetylase inhibitors reactivates HIV-1.
Bouchat S, Delacourt N, Kula A, Darcis G, Van Driessche B, Corazza F, Gatot JS, Melard A, Vanhulle C, Kabeya K, Pardons M, Avettand-Fenoel V, Clumeck N, De Wit S, Rohr O, Rouzioux C, Van Lint C. Bouchat S, et al. Among authors: pardons m. EMBO Mol Med. 2016 Feb 1;8(2):117-38. doi: 10.15252/emmm.201505557. EMBO Mol Med. 2016. PMID: 26681773 Free PMC article.
Correction for Van Gulck et al., "A truncated HIV Tat demonstrates potent and specific latency reversal activity".
Van Gulck E, Pardons M, Nijs E, Verheyen N, Dockx K, Van Den Eynde C, Battivelli E, Vega J, Florence E, Autran B, Archin NM, Margolis DM, Katlama C, Hamimi C, Van Den Wyngaert I, Eyassu F, Vandekerckhove L, Boden D. Van Gulck E, et al. Among authors: pardons m. Antimicrob Agents Chemother. 2024 Aug 7;68(8):e0081924. doi: 10.1128/aac.00819-24. Epub 2024 Jul 2. Antimicrob Agents Chemother. 2024. PMID: 38953623 Free PMC article. No abstract available.
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