Spaan I - Search Results

1

Direct P70S6K1 inhibition to replace dexamethasone in synergistic combination with MCL-1 inhibition in multiple myeloma.

Spaan I, Timmerman LM, Kimman T, Slomp A, Cuenca M, van Nieuwenhuijzen N, Moesbergen LM, Minnema MC, Raymakers RA, Peperzak V. Spaan I, et al. Blood Adv. 2021 Jun 22;5(12):2593-2607. doi: 10.1182/bloodadvances.2020003624. Blood Adv. 2021. PMID: 34152396 Free PMC article.

2

From MGUS to Multiple Myeloma, a Paradigm for Clonal Evolution of Premalignant Cells.

van Nieuwenhuijzen N, Spaan I, Raymakers R, Peperzak V. van Nieuwenhuijzen N, et al. Among authors: spaan i. Cancer Res. 2018 May 15;78(10):2449-2456. doi: 10.1158/0008-5472.CAN-17-3115. Epub 2018 Apr 27. Cancer Res. 2018. PMID: 29703720 Review.

3

Wnt signaling in multiple myeloma: a central player in disease with therapeutic potential.

Spaan I, Raymakers RA, van de Stolpe A, Peperzak V. Spaan I, et al. J Hematol Oncol. 2018 May 18;11(1):67. doi: 10.1186/s13045-018-0615-3. J Hematol Oncol. 2018. PMID: 29776381 Free PMC article. Review.

4

Multiple Myeloma Relapse Is Associated with Increased NFκB Pathway Activity and Upregulation of the Pro-Survival BCL-2 Protein BFL-1.

Spaan I, van de Stolpe A, Raymakers RA, Peperzak V. Spaan I, et al. Cancers (Basel). 2021 Sep 17;13(18):4668. doi: 10.3390/cancers13184668. Cancers (Basel). 2021. PMID: 34572895 Free PMC article.

5

Wnt inhibitors reduce the unfolded protein response and enhance bortezomib-induced cell death in multiple myeloma.

Spaan I, van Nieuwenhuijzen N, Kimman T, Rockx-Brouwer D, Tieland RG, Maurice MM, Minnema MC, Raymakers RA, Peperzak V. Spaan I, et al. Blood Adv. 2023 Apr 11;7(7):1103-1107. doi: 10.1182/bloodadvances.2022008442. Blood Adv. 2023. PMID: 36459495 Free PMC article. No abstract available.

6

Intratumoral platelet aggregate formation in a murine preclinical glioma model depends on podoplanin expression on tumor cells.

Costa B, Eisemann T, Strelau J, Spaan I, Korshunov A, Liu HK, Bugert P, Angel P, Peterziel H. Costa B, et al. Among authors: spaan i. Blood Adv. 2019 Apr 9;3(7):1092-1102. doi: 10.1182/bloodadvances.2018015966. Blood Adv. 2019. PMID: 30948364 Free PMC article.

7

Does coronary resistance change only during systole?

Spaan IJ. Spaan IJ. Circ Res. 1979 Dec;45(6):838-9. doi: 10.1161/01.res.45.6.838. Circ Res. 1979. PMID: 498447 No abstract available.

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