Lima APCA - Search Results

1

Role of the inhibitor of serine peptidase 2 (ISP2) of Trypanosoma brucei rhodesiense in parasite virulence and modulation of the inflammatory responses of the host.

Levy DJ, Goundry A, Laires RSS, Costa TFR, Novo CM, Grab DJ, Mottram JC, Lima APCA. Levy DJ, et al. Among authors: lima apca. PLoS Negl Trop Dis. 2021 Jun 21;15(6):e0009526. doi: 10.1371/journal.pntd.0009526. eCollection 2021 Jun. PLoS Negl Trop Dis. 2021. PMID: 34153047 Free PMC article.

2

The propeptide of cruzipain--a potent selective inhibitor of the trypanosomal enzymes cruzipain and brucipain, and of the human enzyme cathepsin F.

Reis FC, Costa TF, Sulea T, Mezzetti A, Scharfstein J, Brömme D, Ménard R, Lima AP. Reis FC, et al. FEBS J. 2007 Mar;274(5):1224-34. doi: 10.1111/j.1742-4658.2007.05666.x. FEBS J. 2007. PMID: 17298440 Free article.

3

Role of the Trypanosoma brucei natural cysteine peptidase inhibitor ICP in differentiation and virulence.

Santos CC, Coombs GH, Lima AP, Mottram JC. Santos CC, et al. Mol Microbiol. 2007 Nov;66(4):991-1002. doi: 10.1111/j.1365-2958.2007.05970.x. Epub 2007 Oct 17. Mol Microbiol. 2007. PMID: 17944830 Free PMC article.

4

The role of conserved residues of chagasin in the inhibition of cysteine peptidases.

dos Reis FC, Smith BO, Santos CC, Costa TF, Scharfstein J, Coombs GH, Mottram JC, Lima AP. dos Reis FC, et al. FEBS Lett. 2008 Feb 20;582(4):485-90. doi: 10.1016/j.febslet.2008.01.008. Epub 2008 Jan 15. FEBS Lett. 2008. PMID: 18201565 Free PMC article.

5

Influence of parasite encoded inhibitors of serine peptidases in early infection of macrophages with Leishmania major.

Eschenlauer SC, Faria MS, Morrison LS, Bland N, Ribeiro-Gomes FL, DosReis GA, Coombs GH, Lima AP, Mottram JC. Eschenlauer SC, et al. Cell Microbiol. 2009 Jan;11(1):106-20. doi: 10.1111/j.1462-5822.2008.01243.x. Epub 2008 Oct 29. Cell Microbiol. 2009. PMID: 19016791 Free PMC article.

6

Leishmania inhibitor of serine peptidase 2 prevents TLR4 activation by neutrophil elastase promoting parasite survival in murine macrophages.

Faria MS, Reis FC, Azevedo-Pereira RL, Morrison LS, Mottram JC, Lima AP. Faria MS, et al. J Immunol. 2011 Jan 1;186(1):411-22. doi: 10.4049/jimmunol.1002175. Epub 2010 Nov 22. J Immunol. 2011. PMID: 21098233 Free PMC article.

7

Substrate inhibition and allosteric regulation by heparan sulfate of Trypanosoma brucei cathepsin L.

Costa TF, dos Reis FC, Lima AP. Costa TF, et al. Biochim Biophys Acta. 2012 Mar;1824(3):493-501. doi: 10.1016/j.bbapap.2011.12.006. Epub 2012 Jan 3. Biochim Biophys Acta. 2012. PMID: 22234330 Free article.

8

Ecotin-like serine peptidase inhibitor ISP1 of Leishmania major plays a role in flagellar pocket dynamics and promastigote differentiation.

Morrison LS, Goundry A, Faria MS, Tetley L, Eschenlauer SC, Westrop GD, Dostalova A, Volf P, Coombs GH, Lima AP, Mottram JC. Morrison LS, et al. Cell Microbiol. 2012 Aug;14(8):1271-86. doi: 10.1111/j.1462-5822.2012.01798.x. Epub 2012 May 8. Cell Microbiol. 2012. PMID: 22486816 Free PMC article.

9

Role of protein kinase R in the killing of Leishmania major by macrophages in response to neutrophil elastase and TLR4 via TNFα and IFNβ.

Faria MS, Calegari-Silva TC, de Carvalho Vivarini A, Mottram JC, Lopes UG, Lima AP. Faria MS, et al. FASEB J. 2014 Jul;28(7):3050-63. doi: 10.1096/fj.13-245126. Epub 2014 Apr 14. FASEB J. 2014. PMID: 24732131 Free PMC article.

10

Crovirin, a snake venom cysteine-rich secretory protein (CRISP) with promising activity against Trypanosomes and Leishmania.

Adade CM, Carvalho AL, Tomaz MA, Costa TF, Godinho JL, Melo PA, Lima AP, Rodrigues JC, Zingali RB, Souto-Padrón T. Adade CM, et al. PLoS Negl Trop Dis. 2014 Oct 16;8(10):e3252. doi: 10.1371/journal.pntd.0003252. eCollection 2014 Oct. PLoS Negl Trop Dis. 2014. PMID: 25330220 Free PMC article.

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