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Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain.
Shukla S, Ying W, Gray F, Yao Y, Simes ML, Zhao Q, Miao H, Cho HJ, González-Alonso P, Winkler A, Lund G, Purohit T, Kim E, Zhang X, Ray JM, He S, Nikolaidis C, Ndoj J, Wang J, Jaremko Ł, Jaremko M, Ryan RJH, Guzman ML, Grembecka J, Cierpicki T. Shukla S, et al. Among authors: cho hj. Nat Chem Biol. 2021 Jul;17(7):784-793. doi: 10.1038/s41589-021-00815-5. Epub 2021 Jun 21. Nat Chem Biol. 2021. PMID: 34155404 Free PMC article.
Covalent inhibition of NSD1 histone methyltransferase.
Huang H, Howard CA, Zari S, Cho HJ, Shukla S, Li H, Ndoj J, González-Alonso P, Nikolaidis C, Abbott J, Rogawski DS, Potopnyk MA, Kempinska K, Miao H, Purohit T, Henderson A, Mapp A, Sulis ML, Ferrando A, Grembecka J, Cierpicki T. Huang H, et al. Among authors: cho hj. Nat Chem Biol. 2020 Dec;16(12):1403-1410. doi: 10.1038/s41589-020-0626-6. Epub 2020 Aug 31. Nat Chem Biol. 2020. PMID: 32868895 Free PMC article.
Development of potent dimeric inhibitors of GAS41 YEATS domain.
Listunov D, Linhares BM, Kim E, Winkler A, Simes ML, Weaver S, Cho HJ, Rizo A, Zolov S, Keshamouni VG, Grembecka J, Cierpicki T. Listunov D, et al. Among authors: cho hj. Cell Chem Biol. 2021 Dec 16;28(12):1716-1727.e6. doi: 10.1016/j.chembiol.2021.06.010. Epub 2021 Jul 21. Cell Chem Biol. 2021. PMID: 34289376 Free PMC article.
Rationally designed BCL6 inhibitors target activated B cell diffuse large B cell lymphoma.
Cardenas MG, Yu W, Beguelin W, Teater MR, Geng H, Goldstein RL, Oswald E, Hatzi K, Yang SN, Cohen J, Shaknovich R, Vanommeslaeghe K, Cheng H, Liang D, Cho HJ, Abbott J, Tam W, Du W, Leonard JP, Elemento O, Cerchietti L, Cierpicki T, Xue F, MacKerell AD Jr, Melnick AM. Cardenas MG, et al. Among authors: cho hj. J Clin Invest. 2016 Sep 1;126(9):3351-62. doi: 10.1172/JCI85795. Epub 2016 Aug 2. J Clin Invest. 2016. PMID: 27482887 Free PMC article.
Study Protocol of the Korean EGFR Registry: A Multicenter Prospective and Retrospective Cohort Study in Nonsmall Cell Lung Cancer Patients With EGFR Mutation.
Yeo CD, Park DW, Yoon SH, Kim EY, Lee JE, Lee SY, Choi CM, Oh IJ, Kim DJ, Ryu JS, Lee JC, Kim YC, Jang TW, Lee KY, Jang SH, Kim SJ; Korean EGFR Registry Investigators. Yeo CD, et al. Clin Respir J. 2025 Jan;19(1):e70043. doi: 10.1111/crj.70043. Clin Respir J. 2025. PMID: 39757012 Free PMC article.
2,986 results