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NLRP3 (Nucleotide Oligomerization Domain-Like Receptor Family, Pyrin Domain Containing 3)-Caspase-1 Inflammasome Degrades Contractile Proteins: Implications for Aortic Biomechanical Dysfunction and Aneurysm and Dissection Formation.
Wu D, Ren P, Zheng Y, Zhang L, Xu G, Xie W, Lloyd EE, Zhang S, Zhang Q, Curci JA, Coselli JS, Milewicz DM, Shen YH, LeMaire SA. Wu D, et al. Among authors: shen yh. Arterioscler Thromb Vasc Biol. 2017 Apr;37(4):694-706. doi: 10.1161/ATVBAHA.116.307648. Epub 2017 Feb 2. Arterioscler Thromb Vasc Biol. 2017. PMID: 28153878 Free PMC article.
Enigma of Inflammasome Activation by Kinases.
Shen YH, Abe JI. Shen YH, et al. Arterioscler Thromb Vasc Biol. 2019 Aug;39(8):1501-1503. doi: 10.1161/ATVBAHA.119.312965. Epub 2019 Jul 24. Arterioscler Thromb Vasc Biol. 2019. PMID: 31339780 Free PMC article. No abstract available.
Critical Role of Cytosolic DNA and Its Sensing Adaptor STING in Aortic Degeneration, Dissection, and Rupture.
Luo W, Wang Y, Zhang L, Ren P, Zhang C, Li Y, Azares AR, Zhang M, Guo J, Ghaghada KB, Starosolski ZA, Rajapakshe K, Coarfa C, Li Y, Chen R, Fujiwara K, Abe JI, Coselli JS, Milewicz DM, LeMaire SA, Shen YH. Luo W, et al. Among authors: shen yh. Circulation. 2020 Jan 7;141(1):42-66. doi: 10.1161/CIRCULATIONAHA.119.041460. Epub 2019 Dec 30. Circulation. 2020. PMID: 31887080 Free PMC article.
Cholesterol-Induced Phenotypic Modulation of Smooth Muscle Cells to Macrophage/Fibroblast-like Cells Is Driven by an Unfolded Protein Response.
Chattopadhyay A, Kwartler CS, Kaw K, Li Y, Kaw A, Chen J, LeMaire SA, Shen YH, Milewicz DM. Chattopadhyay A, et al. Among authors: shen yh. Arterioscler Thromb Vasc Biol. 2021 Jan;41(1):302-316. doi: 10.1161/ATVBAHA.120.315164. Epub 2020 Oct 8. Arterioscler Thromb Vasc Biol. 2021. PMID: 33028096 Free PMC article.
Early Detection of Aortic Degeneration in a Mouse Model of Sporadic Aortic Aneurysm and Dissection Using Nanoparticle Contrast-Enhanced Computed Tomography.
Ghaghada KB, Ren P, Devkota L, Starosolski Z, Zhang C, Vela D, Stupin IV, Tanifum EA, Annapragada AV, Shen YH, LeMaire SA. Ghaghada KB, et al. Among authors: shen yh. Arterioscler Thromb Vasc Biol. 2021 Apr;41(4):1534-1548. doi: 10.1161/ATVBAHA.120.315210. Epub 2021 Feb 4. Arterioscler Thromb Vasc Biol. 2021. PMID: 33535789 Free PMC article.
Nucleus-mitochondria positive feedback loop formed by ERK5 S496 phosphorylation-mediated poly (ADP-ribose) polymerase activation provokes persistent pro-inflammatory senescent phenotype and accelerates coronary atherosclerosis after chemo-radiation.
Kotla S, Zhang A, Imanishi M, Ko KA, Lin SH, Gi YJ, Moczygemba M, Isgandarova S, Schadler KL, Chung C, Milgrom SA, Banchs J, Yusuf SW, Amaya DN, Guo H, Thomas TN, Shen YH, Deswal A, Herrmann J, Kleinerman ES, Entman ML, Cooke JP, Schifitto G, Maggirwar SB, McBeath E, Gupte AA, Krishnan S, Patel ZS, Yoon Y, Burks JK, Fujiwara K, Brookes PS, Le NT, Hamilton DJ, Abe JI. Kotla S, et al. Among authors: shen yh. Redox Biol. 2021 Nov;47:102132. doi: 10.1016/j.redox.2021.102132. Epub 2021 Sep 20. Redox Biol. 2021. PMID: 34619528 Free PMC article.
594 results