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Kelch-like protein 42 is a profibrotic ubiquitin E3 ligase involved in systemic sclerosis.
Lear TB, Lockwood KC, Larsen M, Tuncer F, Kennerdell JR, Morse C, Valenzi E, Tabib T, Jurczak MJ, Kass DJ, Evankovich JW, Finkel T, Lafyatis R, Liu Y, Chen BB. Lear TB, et al. Among authors: tuncer f. J Biol Chem. 2020 Mar 27;295(13):4171-4180. doi: 10.1074/jbc.AC119.012066. Epub 2020 Feb 17. J Biol Chem. 2020. PMID: 32071084 Free PMC article.
A Fbxo48 inhibitor prevents pAMPKα degradation and ameliorates insulin resistance.
Liu Y, Jurczak MJ, Lear TB, Lin B, Larsen MB, Kennerdell JR, Chen Y, Huckestein BR, Nguyen MK, Tuncer F, Jiang Y, Monga SP, O'Donnell CP, Finkel T, Chen BB, Mallampalli RK. Liu Y, et al. Among authors: tuncer f. Nat Chem Biol. 2021 Mar;17(3):298-306. doi: 10.1038/s41589-020-00723-0. Epub 2021 Jan 25. Nat Chem Biol. 2021. PMID: 33495648 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33506775
Fibronectin-EDA accumulates via reduced ubiquitination downstream of Toll-like receptor 9 activation in SSc-ILD fibroblasts.
Tuncer F, Bulik M, Villandre J, Lear T, Chen Y, Tuncer B, Kass DJ, Valenzi E, Morse C, Sembrat J 2nd, Lafyatis R, Chen B, Evankovich J. Tuncer F, et al. Am J Physiol Lung Cell Mol Physiol. 2022 Oct 1;323(4):L484-L494. doi: 10.1152/ajplung.00019.2022. Epub 2022 Aug 23. Am J Physiol Lung Cell Mol Physiol. 2022. PMID: 35997276 Free PMC article.
65 results