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Synthetic alkyl-ether-lipid promotes TRPV2 channel trafficking trough PI3K/Akt-girdin axis in cancer cells and increases mammary tumour volume.
Guéguinou M, Felix R, Marionneau-Lambot S, Oullier T, Penna A, Kouba S, Gambade A, Fourbon Y, Ternant D, Arnoult C, Simon G, Bouchet AM, Chantôme A, Harnois T, Haelters JP, Jaffrès PA, Weber G, Bougnoux P, Carreaux F, Mignen O, Vandier C, Potier-Cartereau M. Guéguinou M, et al. Cell Calcium. 2021 Jun 12;97:102435. doi: 10.1016/j.ceca.2021.102435. Online ahead of print. Cell Calcium. 2021. PMID: 34167050
Pivotal role of the lipid Raft SK3-Orai1 complex in human cancer cell migration and bone metastases.
Chantôme A, Potier-Cartereau M, Clarysse L, Fromont G, Marionneau-Lambot S, Guéguinou M, Pagès JC, Collin C, Oullier T, Girault A, Arbion F, Haelters JP, Jaffrès PA, Pinault M, Besson P, Joulin V, Bougnoux P, Vandier C. Chantôme A, et al. Cancer Res. 2013 Aug 1;73(15):4852-61. doi: 10.1158/0008-5472.CAN-12-4572. Epub 2013 Jun 17. Cancer Res. 2013. PMID: 23774210
The mechanosensitive TRPV2 calcium channel promotes human melanoma invasiveness and metastatic potential.
Shoji KF, Bayet E, Leverrier-Penna S, Le Devedec D, Mallavialle A, Marionneau-Lambot S, Rambow F, Perret R, Joussaume A, Viel R, Fautrel A, Khammari A, Constantin B, Tartare-Deckert S, Penna A. Shoji KF, et al. Among authors: marionneau lambot s. EMBO Rep. 2023 Apr 5;24(4):e55069. doi: 10.15252/embr.202255069. Epub 2023 Feb 6. EMBO Rep. 2023. PMID: 36744297 Free PMC article.
3-fluoro- and 3,3-difluoro-3,4-dideoxy-KRN7000 analogues as new potent immunostimulator agents: total synthesis and biological evaluation in human invariant natural killer T cells and mice.
Hunault J, Diswall M, Frison JC, Blot V, Rocher J, Marionneau-Lambot S, Oullier T, Douillard JY, Guillarme S, Saluzzo C, Dujardin G, Jacquemin D, Graton J, Le Questel JY, Evain M, Lebreton J, Dubreuil D, Le Pendu J, Pipelier M. Hunault J, et al. J Med Chem. 2012 Feb 9;55(3):1227-41. doi: 10.1021/jm201368m. Epub 2012 Feb 1. J Med Chem. 2012. PMID: 22243602
SCN4B acts as a metastasis-suppressor gene preventing hyperactivation of cell migration in breast cancer.
Bon E, Driffort V, Gradek F, Martinez-Caceres C, Anchelin M, Pelegrin P, Cayuela ML, Marionneau-Lambot S, Oullier T, Guibon R, Fromont G, Gutierrez-Pajares JL, Domingo I, Piver E, Moreau A, Burlaud-Gaillard J, Frank PG, Chevalier S, Besson P, Roger S. Bon E, et al. Nat Commun. 2016 Dec 5;7:13648. doi: 10.1038/ncomms13648. Nat Commun. 2016. PMID: 27917859 Free PMC article.
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