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Synthetic alkyl-ether-lipid promotes TRPV2 channel trafficking trough PI3K/Akt-girdin axis in cancer cells and increases mammary tumour volume.
Guéguinou M, Felix R, Marionneau-Lambot S, Oullier T, Penna A, Kouba S, Gambade A, Fourbon Y, Ternant D, Arnoult C, Simon G, Bouchet AM, Chantôme A, Harnois T, Haelters JP, Jaffrès PA, Weber G, Bougnoux P, Carreaux F, Mignen O, Vandier C, Potier-Cartereau M. Guéguinou M, et al. Among authors: vandier c. Cell Calcium. 2021 Jun 12;97:102435. doi: 10.1016/j.ceca.2021.102435. Online ahead of print. Cell Calcium. 2021. PMID: 34167050
The SK3/K(Ca)2.3 potassium channel is a new cellular target for edelfosine.
Potier M, Chantome A, Joulin V, Girault A, Roger S, Besson P, Jourdan ML, LeGuennec JY, Bougnoux P, Vandier C. Potier M, et al. Among authors: vandier c. Br J Pharmacol. 2011 Jan;162(2):464-79. doi: 10.1111/j.1476-5381.2010.01044.x. Br J Pharmacol. 2011. PMID: 20955368 Free PMC article.
New alkyl-lipid blockers of SK3 channels reduce cancer cell migration and occurrence of metastasis.
Girault A, Haelters JP, Potier-Cartereau M, Chantome A, Pinault M, Marionneau-Lambot S, Oullier T, Simon G, Couthon-Gourvès H, Jaffrès PA, Corbel B, Bougnoux P, Joulin V, Vandier C. Girault A, et al. Among authors: vandier c. Curr Cancer Drug Targets. 2011 Nov;11(9):1111-25. doi: 10.2174/156800911798073069. Curr Cancer Drug Targets. 2011. PMID: 21999627
Targeting SKCa channels in cancer: potential new therapeutic approaches.
Girault A, Haelters JP, Potier-Cartereau M, Chantôme A, Jaffrés PA, Bougnoux P, Joulin V, Vandier C. Girault A, et al. Among authors: vandier c. Curr Med Chem. 2012;19(5):697-713. doi: 10.2174/092986712798992039. Curr Med Chem. 2012. PMID: 22204342 Review.
Pivotal role of the lipid Raft SK3-Orai1 complex in human cancer cell migration and bone metastases.
Chantôme A, Potier-Cartereau M, Clarysse L, Fromont G, Marionneau-Lambot S, Guéguinou M, Pagès JC, Collin C, Oullier T, Girault A, Arbion F, Haelters JP, Jaffrès PA, Pinault M, Besson P, Joulin V, Bougnoux P, Vandier C. Chantôme A, et al. Among authors: vandier c. Cancer Res. 2013 Aug 1;73(15):4852-61. doi: 10.1158/0008-5472.CAN-12-4572. Epub 2013 Jun 17. Cancer Res. 2013. PMID: 23774210
95 results