Wang S - Search Results

1

Discovery of M-1121 as an Orally Active Covalent Inhibitor of Menin-MLL Interaction Capable of Achieving Complete and Long-Lasting Tumor Regression.

Zhang M, Aguilar A, Xu S, Huang L, Chinnaswamy K, Sleger T, Wang B, Gross S, Nicolay BN, Ronseaux S, Harvey K, Wang Y, McEachern D, Kirchhoff PD, Liu Z, Stuckey J, Tron AE, Liu T, Wang S. Zhang M, et al. Among authors: wang y, wang s, wang b. J Med Chem. 2021 Jul 22;64(14):10333-10349. doi: 10.1021/acs.jmedchem.1c00789. Epub 2021 Jul 1. J Med Chem. 2021. PMID: 34196551 Free PMC article.

2

Discovery of substituted 3,4-diphenyl-thiazoles as a novel class of monoamine transporter inhibitors through 3-D pharmacophore search using a new pharmacophore model derived from mazindol.

Enyedy IJ, Wang J, Zaman WA, Johnson KM, Wang S. Enyedy IJ, et al. Among authors: wang j, wang s. Bioorg Med Chem Lett. 2002 Jul 8;12(13):1775-8. doi: 10.1016/s0960-894x(02)00243-3. Bioorg Med Chem Lett. 2002. PMID: 12067559

3

Pharmacophore-based discovery of substituted pyridines as novel dopamine transporter inhibitors.

Enyedy IJ, Sakamuri S, Zaman WA, Johnson KM, Wang S. Enyedy IJ, et al. Among authors: wang s. Bioorg Med Chem Lett. 2003 Feb 10;13(3):513-7. doi: 10.1016/s0960-894x(02)00943-5. Bioorg Med Chem Lett. 2003. PMID: 12565962

4

Comparative evaluation of 11 scoring functions for molecular docking.

Wang R, Lu Y, Wang S. Wang R, et al. Among authors: wang s. J Med Chem. 2003 Jun 5;46(12):2287-303. doi: 10.1021/jm0203783. J Med Chem. 2003. PMID: 12773034

5

Molecular modeling of the three-dimensional structure of dopamine 3 (D3) subtype receptor: discovery of novel and potent D3 ligands through a hybrid pharmacophore- and structure-based database searching approach.

Varady J, Wu X, Fang X, Min J, Hu Z, Levant B, Wang S. Varady J, et al. Among authors: wang s. J Med Chem. 2003 Oct 9;46(21):4377-92. doi: 10.1021/jm030085p. J Med Chem. 2003. PMID: 14521403

6

Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database.

Nikolovska-Coleska Z, Xu L, Hu Z, Tomita Y, Li P, Roller PP, Wang R, Fang X, Guo R, Zhang M, Lippman ME, Yang D, Wang S. Nikolovska-Coleska Z, et al. Among authors: wang s, wang r. J Med Chem. 2004 May 6;47(10):2430-40. doi: 10.1021/jm030420+. J Med Chem. 2004. PMID: 15115387

7

Structure-based design, synthesis, and evaluation of conformationally constrained mimetics of the second mitochondria-derived activator of caspase that target the X-linked inhibitor of apoptosis protein/caspase-9 interaction site.

Sun H, Nikolovska-Coleska Z, Yang CY, Xu L, Tomita Y, Krajewski K, Roller PP, Wang S. Sun H, et al. Among authors: wang s. J Med Chem. 2004 Aug 12;47(17):4147-50. doi: 10.1021/jm0499108. J Med Chem. 2004. PMID: 15293984

8

Development and optimization of a binding assay for the XIAP BIR3 domain using fluorescence polarization.

Nikolovska-Coleska Z, Wang R, Fang X, Pan H, Tomita Y, Li P, Roller PP, Krajewski K, Saito NG, Stuckey JA, Wang S. Nikolovska-Coleska Z, et al. Among authors: wang s, wang r. Anal Biochem. 2004 Sep 15;332(2):261-73. doi: 10.1016/j.ab.2004.05.055. Anal Biochem. 2004. PMID: 15325294

9

Design, synthesis, and evaluation of hexahydrobenz[f]isoquinolines as a novel class of dopamine 3 receptor ligands.

Wu X, Chen J, Ji M, Varady J, Levant B, Wang S. Wu X, et al. Among authors: wang s. Bioorg Med Chem Lett. 2004 Dec 6;14(23):5813-6. doi: 10.1016/j.bmcl.2004.09.047. Bioorg Med Chem Lett. 2004. PMID: 15501046

10

Structure-based design, synthesis and biochemical testing of novel and potent Smac peptido-mimetics.

Sun H, Nikolovska-Coleska Z, Chen J, Yang CY, Tomita Y, Pan H, Yoshioka Y, Krajewski K, Roller PP, Wang S. Sun H, et al. Among authors: wang s. Bioorg Med Chem Lett. 2005 Feb 1;15(3):793-7. doi: 10.1016/j.bmcl.2004.11.008. Bioorg Med Chem Lett. 2005. PMID: 15664859

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