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Synthesis and evaluation of new designed multiple ligands directed towards both peroxisome proliferator-activated receptor-γ and angiotensin II type 1 receptor.
Meyer M, Foulquier S, Dupuis F, Flament S, Grimaud L, Henrion D, Lartaud I, Monard G, Grillier-Vuissoz I, Boisbrun M. Meyer M, et al. Among authors: boisbrun m. Eur J Med Chem. 2018 Oct 5;158:334-352. doi: 10.1016/j.ejmech.2018.08.082. Epub 2018 Aug 31. Eur J Med Chem. 2018. PMID: 30223121 Free article.
AB186 Inhibits Migration of Triple-Negative Breast Cancer Cells and Interacts with α-Tubulin.
Geoffroy M, Lemesle M, Kleinclauss A, Mazerbourg S, Batista L, Barberi-Heyob M, Bastogne T, Boireau W, Rouleau A, Dupommier D, Boisbrun M, Comoy C, Flament S, Grillier-Vuissoz I, Kuntz S. Geoffroy M, et al. Among authors: boisbrun m. Int J Mol Sci. 2022 Jun 20;23(12):6859. doi: 10.3390/ijms23126859. Int J Mol Sci. 2022. PMID: 35743305 Free PMC article.
Synthesis and Pharmacological Characterization of Fluorescent Ligands Targeting the Angiotensin II Receptors Derived from Agonists, β-Arrestin-Biased Agonists, and Antagonists.
Delaitre C, Boisbrun M, Acherar S, Dias A, Kleinclauss A, Achard M, Colin M, Nguyen TM, Humbert N, Chmeis K, Martinez KL, Gilles N, Robin P, Lecat S, Dupuis F. Delaitre C, et al. Among authors: boisbrun m. J Med Chem. 2024 Nov 28;67(22):20275-20297. doi: 10.1021/acs.jmedchem.4c01693. Epub 2024 Nov 11. J Med Chem. 2024. PMID: 39526976
New troglitazone derivatives devoid of PPARγ agonist activity display an increased antiproliferative effect in both hormone-dependent and hormone-independent breast cancer cell lines.
Colin C, Salamone S, Grillier-Vuissoz I, Boisbrun M, Kuntz S, Lecomte J, Chapleur Y, Flament S. Colin C, et al. Among authors: boisbrun m. Breast Cancer Res Treat. 2010 Nov;124(1):101-10. doi: 10.1007/s10549-009-0700-y. Epub 2010 Jan 7. Breast Cancer Res Treat. 2010. PMID: 20054646
Mono- and bis-thiazolium salts have potent antimalarial activity.
Hamzé A, Rubi E, Arnal P, Boisbrun M, Carcel C, Salom-Roig X, Maynadier M, Wein S, Vial H, Calas M. Hamzé A, et al. Among authors: boisbrun m. J Med Chem. 2005 May 19;48(10):3639-43. doi: 10.1021/jm0492608. J Med Chem. 2005. PMID: 15887971
33 results