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p53 Nongenotoxic Activation and mTORC1 Inhibition Lead to Effective Combination for Neuroblastoma Therapy.
Moreno-Smith M, Lakoma A, Chen Z, Tao L, Scorsone KA, Schild L, Aviles-Padilla K, Nikzad R, Zhang Y, Chakraborty R, Molenaar JJ, Vasudevan SA, Sheehan V, Kim ES, Paust S, Shohet JM, Barbieri E. Moreno-Smith M, et al. Clin Cancer Res. 2017 Nov 1;23(21):6629-6639. doi: 10.1158/1078-0432.CCR-17-0668. Epub 2017 Aug 18. Clin Cancer Res. 2017. PMID: 28821555 Free PMC article.
Dual targeting of MDM2 and BCL2 as a therapeutic strategy in neuroblastoma.
Van Goethem A, Yigit N, Moreno-Smith M, Vasudevan SA, Barbieri E, Speleman F, Shohet J, Vandesompele J, Van Maerken T. Van Goethem A, et al. Oncotarget. 2017 Jul 4;8(34):57047-57057. doi: 10.18632/oncotarget.18982. eCollection 2017 Aug 22. Oncotarget. 2017. PMID: 28915653 Free PMC article.
The synergy of BET inhibitors with aurora A kinase inhibitors in MYCN-amplified neuroblastoma is heightened with functional TP53.
Yi JS, Sias-Garcia O, Nasholm N, Hu X, Iniguez AB, Hall MD, Davis M, Guha R, Moreno-Smith M, Barbieri E, Duong K, Koach J, Qi J, Bradner JE, Stegmaier K, Weiss WA, Gustafson WC. Yi JS, et al. Among authors: moreno smith m. Neoplasia. 2021 Jun;23(6):624-633. doi: 10.1016/j.neo.2021.05.003. Epub 2021 Jun 7. Neoplasia. 2021. PMID: 34107377 Free PMC article.
Restoration of the molecular clock is tumor suppressive in neuroblastoma.
Moreno-Smith M, Milazzo G, Tao L, Fekry B, Zhu B, Mohammad MA, Di Giacomo S, Borkar R, Reddy KRK, Capasso M, Vasudevan SA, Sumazin P, Hicks J, Putluri N, Perini G, Eckel-Mahan K, Burris TP, Barbieri E. Moreno-Smith M, et al. Nat Commun. 2021 Jun 28;12(1):4006. doi: 10.1038/s41467-021-24196-4. Nat Commun. 2021. PMID: 34183658 Free PMC article.
CHAF1A Blocks Neuronal Differentiation and Promotes Neuroblastoma Oncogenesis via Metabolic Reprogramming.
Tao L, Moreno-Smith M, Ibarra-García-Padilla R, Milazzo G, Drolet NA, Hernandez BE, Oh YS, Patel I, Kim JJ, Zorman B, Patel T, Kamal AHM, Zhao Y, Hicks J, Vasudevan SA, Putluri N, Coarfa C, Sumazin P, Perini G, Parchem RJ, Uribe RA, Barbieri E. Tao L, et al. Among authors: moreno smith m. Adv Sci (Weinh). 2021 Oct;8(19):e2005047. doi: 10.1002/advs.202005047. Epub 2021 Aug 8. Adv Sci (Weinh). 2021. PMID: 34365742 Free PMC article.
MYCN-driven fatty acid uptake is a metabolic vulnerability in neuroblastoma.
Tao L, Mohammad MA, Milazzo G, Moreno-Smith M, Patel TD, Zorman B, Badachhape A, Hernandez BE, Wolf AB, Zeng Z, Foster JH, Aloisi S, Sumazin P, Zu Y, Hicks J, Ghaghada KB, Putluri N, Perini G, Coarfa C, Barbieri E. Tao L, et al. Among authors: moreno smith m. Nat Commun. 2022 Jun 28;13(1):3728. doi: 10.1038/s41467-022-31331-2. Nat Commun. 2022. PMID: 35764645 Free PMC article.
Longitudinal evaluation of serum microRNAs as biomarkers for neuroblastoma burden and therapeutic p53 reactivation.
Van Goethem A, Deleu J, Yigit N, Everaert C, Moreno-Smith M, Vasudevan SA, Zeka F, Demuynck F, Barbieri E, Speleman F, Mestdagh P, Shohet J, Vandesompele J, Van Maerken T. Van Goethem A, et al. Among authors: moreno smith m. NAR Cancer. 2023 Jan 18;5(1):zcad002. doi: 10.1093/narcan/zcad002. eCollection 2023 Mar. NAR Cancer. 2023. PMID: 36683916 Free PMC article.
Biologic effects of dopamine on tumor vasculature in ovarian carcinoma.
Moreno-Smith M, Lee SJ, Lu C, Nagaraja AS, He G, Rupaimoole R, Han HD, Jennings NB, Roh JW, Nishimura M, Kang Y, Allen JK, Armaiz GN, Matsuo K, Shahzad MM, Bottsford-Miller J, Langley RR, Cole SW, Lutgendorf SK, Siddik ZH, Sood AK. Moreno-Smith M, et al. Neoplasia. 2013 May;15(5):502-10. doi: 10.1593/neo.121412. Neoplasia. 2013. PMID: 23633922 Free PMC article.
24 results