Li H - Search Results

1

Identification and Characterization of Polysorbate-Degrading Enzymes in a Monoclonal Antibody Formulation.

Graf T, Tomlinson A, Yuk IH, Kufer R, Spensberger B, Falkenstein R, Shen A, Li H, Duan D, Liu W, Wohlrab S, Edelmann F, Leiss M. Graf T, et al. Among authors: li h. J Pharm Sci. 2021 Nov;110(11):3558-3567. doi: 10.1016/j.xphs.2021.06.033. Epub 2021 Jul 2. J Pharm Sci. 2021. PMID: 34224732

2

Versatile LC-MS-Based Workflow with Robust 0.1 ppm Sensitivity for Identifying Residual HCPs in Biotherapeutic Products.

Yang F, Li D, Kufer R, Cadang L, Zhang J, Dai L, Guo J, Wohlrab S, Greenwood-Goodwin M, Shen A, Duan D, Li H, Yuk IH. Yang F, et al. Among authors: li d, li h. Anal Chem. 2022 Jan 18;94(2):723-731. doi: 10.1021/acs.analchem.1c03095. Epub 2021 Dec 18. Anal Chem. 2022. PMID: 34927411

3

Characterization of Recombinantly-Expressed Hydrolytic Enzymes from Chinese Hamster Ovary Cells: Identification of Host Cell Proteins that Degrade Polysorbate.

Kovner D, Yuk IH, Shen A, Li H, Graf T, Gupta S, Liu W, Tomlinson A. Kovner D, et al. Among authors: li h. J Pharm Sci. 2023 May;112(5):1351-1363. doi: 10.1016/j.xphs.2023.01.003. Epub 2023 Jan 14. J Pharm Sci. 2023. PMID: 36646283

4

Characterization of antibody variants during process development: the tale of incomplete processing of N-terminal secretion peptide.

Ambrogelly A, Liu YH, Li H, Mengisen S, Yao B, Xu W, Cannon-Carlson S. Ambrogelly A, et al. Among authors: li h. MAbs. 2012 Nov-Dec;4(6):701-9. doi: 10.4161/mabs.21614. Epub 2012 Aug 29. MAbs. 2012. PMID: 22932441 Free PMC article.

5

The measurement and control of high-risk host cell proteins for polysorbate degradation in biologics formulation.

Li X, Wang F, Li H, Richardson DD, Roush DJ. Li X, et al. Among authors: li h. Antib Ther. 2022 Jan 15;5(1):42-54. doi: 10.1093/abt/tbac002. eCollection 2022 Jan. Antib Ther. 2022. PMID: 35155990 Free PMC article. Review.

6

Definition and dynamic control of a continuous chromatography process independent of cell culture titer and impurities.

Chmielowski RA, Mathiasson L, Blom H, Go D, Ehring H, Khan H, Li H, Cutler C, Lacki K, Tugcu N, Roush D. Chmielowski RA, et al. Among authors: li h. J Chromatogr A. 2017 Dec 1;1526:58-69. doi: 10.1016/j.chroma.2017.10.030. Epub 2017 Oct 13. J Chromatogr A. 2017. PMID: 29078985

7

Establishment and validation of predictive model of ARDS in critically ill patients.

Wei S, Zhang H, Li H, Li C, Shen Z, Yin Y, Cong Z, Zeng Z, Ge Q, Li D, Zhu X. Wei S, et al. Among authors: li h. J Transl Med. 2025 Jan 13;23(1):64. doi: 10.1186/s12967-024-06054-1. J Transl Med. 2025. PMID: 39806409

8

Impacts of genomic alterations on the efficacy of HER2-targeted antibody-drug conjugates in patients with metastatic breast cancer.

Huang R, Hu A, Rong Q, Shu D, Chen M, Yang W, Zhang Y, Zheng Q, An X, Xue C, Li H, Shi Y. Huang R, et al. Among authors: li h. J Transl Med. 2025 Jan 13;23(1):63. doi: 10.1186/s12967-025-06082-5. J Transl Med. 2025. PMID: 39806366

9

A humanized anti-MSLN×4-1BB bispecific antibody exhibits potent antitumour activity through 4-1BB signaling activation and fc function without systemic toxicity.

Zhang DY, Zhang ZH, Liu WT, Zhou WM, Zhou PF, Wei JJ, Dai XJ, Zeng XL, Zhou YQ, Li HW, Zhang H, Shen AL, Cheng LS, Shen GD, He YF. Zhang DY, et al. Among authors: li hw. J Transl Med. 2025 Jan 13;23(1):53. doi: 10.1186/s12967-025-06107-z. J Transl Med. 2025. PMID: 39806351

10

Mechanisms of mitochondrial damage-associated molecular patterns associated with inflammatory response in cardiovascular diseases.

Guan X, Li H, Zhang L, Zhi H. Guan X, et al. Among authors: li h. Inflamm Res. 2025 Jan 13;74(1):18. doi: 10.1007/s00011-025-01993-x. Inflamm Res. 2025. PMID: 39806203 Review.

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