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Tetralone derivatives are MIF tautomerase inhibitors and attenuate macrophage activation and amplify the hypothermic response in endotoxemic mice.
Garai J, Krekó M, Őrfi L, Jakus PB, Rumbus Z, Kéringer P, Garami A, Vámos E, Kovács D, Bagóné Vántus V, Radnai B, Lóránd T. Garai J, et al. Among authors: kovacs d. J Enzyme Inhib Med Chem. 2021 Dec;36(1):1357-1369. doi: 10.1080/14756366.2021.1916010. J Enzyme Inhib Med Chem. 2021. PMID: 34225560 Free PMC article.
Modulation of Mitochondrial Quality Control Processes by BGP-15 in Oxidative Stress Scenarios: From Cell Culture to Heart Failure.
Horvath O, Ordog K, Bruszt K, Kalman N, Kovacs D, Radnai B, Gallyas F, Toth K, Halmosi R, Deres L. Horvath O, et al. Among authors: kovacs d. Oxid Med Cell Longev. 2021 Feb 27;2021:6643871. doi: 10.1155/2021/6643871. eCollection 2021. Oxid Med Cell Longev. 2021. Retraction in: Oxid Med Cell Longev. 2023 Oct 11;2023:9864208. doi: 10.1155/2023/9864208 PMID: 33728024 Free PMC article. Retracted.
Synthesis and evaluation of a new class of MIF-inhibitors in activated macrophage cells and in experimental septic shock in mice.
Garai J, Radnai B, Vámos E, Kovács D, Vántus VB, Rumbus Z, Pákai E, Garami A, Gulyás-Fekete G, Agócs A, Krekó M, Zaman K, Prókai L, Őrfi L, Jakus PB, Lóránd T. Garai J, et al. Among authors: kovacs d. Eur J Med Chem. 2023 Feb 5;247:115050. doi: 10.1016/j.ejmech.2022.115050. Epub 2022 Dec 28. Eur J Med Chem. 2023. PMID: 36587420 Free article.
Activation of mitochondrial fusion provides a new treatment for mitochondria-related diseases.
Szabo A, Sumegi K, Fekete K, Hocsak E, Debreceni B, Setalo G Jr, Kovacs K, Deres L, Kengyel A, Kovacs D, Mandl J, Nyitrai M, Febbraio MA, Gallyas F Jr, Sumegi B. Szabo A, et al. Among authors: kovacs d, kovacs k. Biochem Pharmacol. 2018 Apr;150:86-96. doi: 10.1016/j.bcp.2018.01.038. Epub 2018 Feb 3. Biochem Pharmacol. 2018. PMID: 29378182 Free article.
429 results