Siradze K - Search Results

1

An integrated approach for characterizing immunogenic responses toward a bispecific antibody.

Cohen S, Chung S, Spiess C, Lundin V, Stefanich E, Laing ST, Clark V, Brumm J, Zhou Y, Huang C, Guerrero J, Myneni S, Yadav R, Siradze K, Peng K. Cohen S, et al. Among authors: siradze k. MAbs. 2021 Jan-Dec;13(1):1944017. doi: 10.1080/19420862.2021.1944017. MAbs. 2021. PMID: 34225571 Free PMC article.

2

Clinical immunogenicity specificity assessments: a platform evaluation.

Peng K, Siradze K, Quarmby V, Fischer SK. Peng K, et al. Among authors: siradze k. J Pharm Biomed Anal. 2011 Feb 20;54(3):629-35. doi: 10.1016/j.jpba.2010.09.035. Epub 2010 Oct 29. J Pharm Biomed Anal. 2011. PMID: 21035975

3

Measurement of IL-17AA and IL-17FF as Pharmacodynamic Biomarkers to Demonstrate Target Engagement in the Phase I Study of MCAF5352A.

Peng K, Wang Y, Siradze K, Erickson R, Fischer SK, Staton TL. Peng K, et al. Among authors: siradze k. AAPS J. 2018 Dec 13;21(1):9. doi: 10.1208/s12248-018-0280-z. AAPS J. 2018. PMID: 30547287 Clinical Trial.

4

Characterization of robust immune responses to a bispecific antibody, a novel class of antibody therapeutics.

Peng K, Siradze K, Fischer SK. Peng K, et al. Among authors: siradze k. Bioanalysis. 2021 Feb;13(4):239-252. doi: 10.4155/bio-2020-0281. Epub 2021 Feb 12. Bioanalysis. 2021. PMID: 33576267

5

Successful Development of Nonclinical Anti-Drug Antibody Assays to Support Zinpentraxin Alfa Reproductive Toxicology Studies.

Arjomandi A, Siradze K, Cheu M, Davancaze T, Yadav R, Rao GK, Wong L, Fischer SK. Arjomandi A, et al. Among authors: siradze k. AAPS J. 2024 Jan 24;26(1):16. doi: 10.1208/s12248-024-00891-0. AAPS J. 2024. PMID: 38267613

6

A generic anti-drug antibody assay for monoclonal antibody therapeutics with broad dynamic range eliminates the need for titer evaluation in preclinical studies.

Li H, Foley AR, Shim J, Siradze K, Webb-Vargas Y, Sperinde G, Fischer SK. Li H, et al. Among authors: siradze k. J Pharm Biomed Anal. 2024 Oct 15;249:116364. doi: 10.1016/j.jpba.2024.116364. Epub 2024 Jul 15. J Pharm Biomed Anal. 2024. PMID: 39047461

7

Evaluation of multiple immunoassay formats for detection of anti-drug antibodies to zinpentraxin alfa.

Yang X, Siradze K, Sperinde G, Arjomandi A, Fischer S. Yang X, et al. Among authors: siradze k. J Immunol Methods. 2023 Nov;522:113573. doi: 10.1016/j.jim.2023.113573. Epub 2023 Oct 9. J Immunol Methods. 2023. PMID: 37816404

8

Relation of increased prebeta-1 high-density lipoprotein levels to risk of coronary heart disease.

Guey LT, Pullinger CR, Ishida BY, O'Connor PM, Zellner C, Francone OL, Laramie JM, Naya-Vigne JM, Siradze KA, Deedwania P, Redberg RF, Frost PH, Seymour AB, Kane JP, Malloy MJ. Guey LT, et al. Among authors: siradze ka. Am J Cardiol. 2011 Aug 1;108(3):360-6. doi: 10.1016/j.amjcard.2011.03.054. Am J Cardiol. 2011. PMID: 21757044

9

Elevated baseline triglyceride levels modulate effects of HMGCoA reductase inhibitors on plasma lipoproteins.

Drmanac S, Heilbron DC, Pullinger CR, Jafari M, Gietzen D, Ukrainczyk T, Cho MH, Frost PH, Siradze K, Drmanac RT, Kane JP, Malloy MJ. Drmanac S, et al. Among authors: siradze k. J Cardiovasc Pharmacol Ther. 2001 Jan;6(1):47-56. doi: 10.1177/107424840100600106. J Cardiovasc Pharmacol Ther. 2001. PMID: 11452336

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