Rodrigues T - Search Results

1

Augmenting Adaptive Machine Learning with Kinetic Modeling for Reaction Optimization.

Almeida AF, Ataíde FAP, Loureiro RMS, Moreira R, Rodrigues T. Almeida AF, et al. Among authors: rodrigues t. J Org Chem. 2021 Oct 15;86(20):14192-14198. doi: 10.1021/acs.joc.1c01038. Epub 2021 Jul 8. J Org Chem. 2021. PMID: 34235919

2

Unanticipated acyloxymethylation of sumatriptan indole nitrogen atom and its implications in prodrug design.

Rodrigues T, Moreira R, Guedes RC, Iley J, Lopes F. Rodrigues T, et al. Arch Pharm (Weinheim). 2008 Jun;341(6):344-50. doi: 10.1002/ardp.200700250. Arch Pharm (Weinheim). 2008. PMID: 18442019

3

Design, synthesis and structure-activity relationships of (1H-pyridin-4-ylidene)amines as potential antimalarials.

Rodrigues T, Guedes RC, dos Santos DJ, Carrasco M, Gut J, Rosenthal PJ, Moreira R, Lopes F. Rodrigues T, et al. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3476-80. doi: 10.1016/j.bmcl.2009.05.017. Epub 2009 May 9. Bioorg Med Chem Lett. 2009. PMID: 19467600

4

Inhibitors of the mitochondrial electron transport chain and de novo pyrimidine biosynthesis as antimalarials: The present status.

Rodrigues T, Lopes F, Moreira R. Rodrigues T, et al. Curr Med Chem. 2010;17(10):929-56. doi: 10.2174/092986710790820660. Curr Med Chem. 2010. PMID: 20156168 Review.

5

New hope in the fight against malaria?

Rodrigues T, Moreira R, Lopes F. Rodrigues T, et al. Future Med Chem. 2011 Jan;3(1):1-3. doi: 10.4155/fmc.10.274. Future Med Chem. 2011. PMID: 21428820 No abstract available.

6

Identification of new antimalarial leads by use of virtual screening against cytochrome bc₁.

Rodrigues T, Moreira R, Gut J, Rosenthal PJ, O Neill PM, Biagini GA, Lopes F, dos Santos DJ, Guedes RC. Rodrigues T, et al. Bioorg Med Chem. 2011 Nov 1;19(21):6302-8. doi: 10.1016/j.bmc.2011.09.004. Epub 2011 Sep 10. Bioorg Med Chem. 2011. PMID: 21958736

7

Targeting the liver stage of malaria parasites: a yet unmet goal.

Rodrigues T, Prudêncio M, Moreira R, Mota MM, Lopes F. Rodrigues T, et al. J Med Chem. 2012 Feb 9;55(3):995-1012. doi: 10.1021/jm201095h. Epub 2011 Dec 21. J Med Chem. 2012. PMID: 22122518 Review. No abstract available.

8

Drug screen targeted at Plasmodium liver stages identifies a potent multistage antimalarial drug.

da Cruz FP, Martin C, Buchholz K, Lafuente-Monasterio MJ, Rodrigues T, Sönnichsen B, Moreira R, Gamo FJ, Marti M, Mota MM, Hannus M, Prudêncio M. da Cruz FP, et al. Among authors: rodrigues t. J Infect Dis. 2012 Apr 15;205(8):1278-86. doi: 10.1093/infdis/jis184. Epub 2012 Mar 6. J Infect Dis. 2012. PMID: 22396598 Free PMC article.

9

Quinolin-4(1H)-imines are potent antiplasmodial drugs targeting the liver stage of malaria.

Rodrigues T, da Cruz FP, Lafuente-Monasterio MJ, Gonçalves D, Ressurreição AS, Sitoe AR, Bronze MR, Gut J, Schneider G, Mota MM, Rosenthal PJ, Prudêncio M, Gamo FJ, Lopes F, Moreira R. Rodrigues T, et al. J Med Chem. 2013 Jun 13;56(11):4811-5. doi: 10.1021/jm400246e. Epub 2013 May 23. J Med Chem. 2013. PMID: 23701465

10

Flavones as isosteres of 4(1H)-quinolones: discovery of ligand efficient and dual stage antimalarial lead compounds.

Rodrigues T, Ressurreição AS, da Cruz FP, Albuquerque IS, Gut J, Carrasco MP, Gonçalves D, Guedes RC, dos Santos DJ, Mota MM, Rosenthal PJ, Moreira R, Prudêncio M, Lopes F. Rodrigues T, et al. Eur J Med Chem. 2013 Nov;69:872-80. doi: 10.1016/j.ejmech.2013.09.008. Epub 2013 Sep 20. Eur J Med Chem. 2013. PMID: 24125849

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