Douek DC - Search Results

1

Translocated microbiome composition determines immunological outcome in treated HIV infection.

Nganou-Makamdop K, Talla A, Sharma AA, Darko S, Ransier A, Laboune F, Chipman JG, Beilman GJ, Hoskuldsson T, Fourati S, Schmidt TE, Arumugam S, Lima NS, Moon D, Callisto S, Schoephoerster J, Tomalka J, Mugyenyi P, Ssali F, Muloma P, Ssengendo P, Leda AR, Cheu RK, Flynn JK, Morou A, Brunet-Ratnasingham E, Rodriguez B, Lederman MM, Kaufmann DE, Klatt NR, Kityo C, Brenchley JM, Schacker TW, Sekaly RP, Douek DC. Nganou-Makamdop K, et al. Among authors: douek dc. Cell. 2021 Jul 22;184(15):3899-3914.e16. doi: 10.1016/j.cell.2021.05.023. Epub 2021 Jul 7. Cell. 2021. PMID: 34237254 Free PMC article.

2

Poor CD4 T cell restoration after suppression of HIV-1 replication may reflect lower thymic function.

Teixeira L, Valdez H, McCune JM, Koup RA, Badley AD, Hellerstein MK, Napolitano LA, Douek DC, Mbisa G, Deeks S, Harris JM, Barbour JD, Gross BH, Francis IR, Halvorsen R, Asaad R, Lederman MM. Teixeira L, et al. Among authors: douek dc. AIDS. 2001 Sep 28;15(14):1749-56. doi: 10.1097/00002030-200109280-00002. AIDS. 2001. PMID: 11579235

3

Analysis of total human immunodeficiency virus (HIV)-specific CD4(+) and CD8(+) T-cell responses: relationship to viral load in untreated HIV infection.

Betts MR, Ambrozak DR, Douek DC, Bonhoeffer S, Brenchley JM, Casazza JP, Koup RA, Picker LJ. Betts MR, et al. Among authors: douek dc. J Virol. 2001 Dec;75(24):11983-91. doi: 10.1128/JVI.75.24.11983-11991.2001. J Virol. 2001. PMID: 11711588 Free PMC article.

4

A novel approach to the analysis of specificity, clonality, and frequency of HIV-specific T cell responses reveals a potential mechanism for control of viral escape.

Douek DC, Betts MR, Brenchley JM, Hill BJ, Ambrozak DR, Ngai KL, Karandikar NJ, Casazza JP, Koup RA. Douek DC, et al. J Immunol. 2002 Mar 15;168(6):3099-104. doi: 10.4049/jimmunol.168.6.3099. J Immunol. 2002. PMID: 11884484

5

HIV preferentially infects HIV-specific CD4+ T cells.

Douek DC, Brenchley JM, Betts MR, Ambrozak DR, Hill BJ, Okamoto Y, Casazza JP, Kuruppu J, Kunstman K, Wolinsky S, Grossman Z, Dybul M, Oxenius A, Price DA, Connors M, Koup RA. Douek DC, et al. Nature. 2002 May 2;417(6884):95-8. doi: 10.1038/417095a. Nature. 2002. PMID: 11986671

6

Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells.

Brenchley JM, Karandikar NJ, Betts MR, Ambrozak DR, Hill BJ, Crotty LE, Casazza JP, Kuruppu J, Migueles SA, Connors M, Roederer M, Douek DC, Koup RA. Brenchley JM, et al. Among authors: douek dc. Blood. 2003 Apr 1;101(7):2711-20. doi: 10.1182/blood-2002-07-2103. Epub 2002 Nov 14. Blood. 2003. PMID: 12433688 Free article.

7

Expansion of activated human naïve T-cells precedes effector function.

Brenchley JM, Douek DC, Ambrozak DR, Chatterji M, Betts MR, Davis LS, Koup RA. Brenchley JM, et al. Among authors: douek dc. Clin Exp Immunol. 2002 Dec;130(3):432-40. doi: 10.1046/j.1365-2249.2002.02015.x. Clin Exp Immunol. 2002. PMID: 12452833 Free PMC article.

8

T cells containing T cell receptor excision circles are inversely related to HIV replication and are selectively and rapidly released into circulation with antiretroviral treatment.

Diaz M, Douek DC, Valdez H, Hill BJ, Peterson D, Sanne I, Piliero PJ, Koup RA, Green SB, Schnittman S, Lederman MM. Diaz M, et al. Among authors: douek dc. AIDS. 2003 May 23;17(8):1145-9. doi: 10.1097/00002030-200305230-00005. AIDS. 2003. PMID: 12819515

9

Sometimes help may not be enough.

Lederman MM, Douek DC. Lederman MM, et al. Among authors: douek dc. AIDS. 2003 May 23;17(8):1249-51. doi: 10.1097/00002030-200305230-00018. AIDS. 2003. PMID: 12819528 No abstract available.

10

Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation.

Betts MR, Brenchley JM, Price DA, De Rosa SC, Douek DC, Roederer M, Koup RA. Betts MR, et al. Among authors: douek dc. J Immunol Methods. 2003 Oct 1;281(1-2):65-78. doi: 10.1016/s0022-1759(03)00265-5. J Immunol Methods. 2003. PMID: 14580882

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