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Page 1
Thousands of induced germline mutations affecting immune cells identified by automated meiotic mapping coupled with machine learning.
Xu D, Lyon S, Bu CH, Hildebrand S, Choi JH, Zhong X, Liu A, Turer EE, Zhang Z, Russell J, Ludwig S, Mahrt E, Nair-Gill E, Shi H, Wang Y, Zhang D, Yue T, Wang KW, SoRelle JA, Su L, Misawa T, McAlpine W, Sun L, Wang J, Zhan X, Choi M, Farokhnia R, Sakla A, Schneider S, Coco H, Coolbaugh G, Hayse B, Mazal S, Medler D, Nguyen B, Rodriguez E, Wadley A, Tang M, Li X, Anderton P, Keller K, Press A, Scott L, Quan J, Cooper S, Collie T, Qin B, Cardin J, Simpson R, Tadesse M, Sun Q, Wise CA, Rios JJ, Moresco EMY, Beutler B. Xu D, et al. Among authors: sorelle ja. Proc Natl Acad Sci U S A. 2021 Jul 13;118(28):e2106786118. doi: 10.1073/pnas.2106786118. Proc Natl Acad Sci U S A. 2021. PMID: 34260399 Free PMC article.
Real-time resolution of point mutations that cause phenovariance in mice.
Wang T, Zhan X, Bu CH, Lyon S, Pratt D, Hildebrand S, Choi JH, Zhang Z, Zeng M, Wang KW, Turer E, Chen Z, Zhang D, Yue T, Wang Y, Shi H, Wang J, Sun L, SoRelle J, McAlpine W, Hutchins N, Zhan X, Fina M, Gobert R, Quan J, Kreutzer M, Arnett S, Hawkins K, Leach A, Tate C, Daniel C, Reyna C, Prince L, Davis S, Purrington J, Bearden R, Weatherly J, White D, Russell J, Sun Q, Tang M, Li X, Scott L, Moresco EM, McInerney GM, Karlsson Hedestam GB, Xie Y, Beutler B. Wang T, et al. Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):E440-9. doi: 10.1073/pnas.1423216112. Epub 2015 Jan 20. Proc Natl Acad Sci U S A. 2015. PMID: 25605905 Free PMC article.
Intracellular lipid metabolism impairs β cell compensation during diet-induced obesity.
Ye R, Gordillo R, Shao M, Onodera T, Chen Z, Chen S, Lin X, SoRelle JA, Li X, Tang M, Keller MP, Kuliawat R, Attie AD, Gupta RK, Holland WL, Beutler B, Herz J, Scherer PE. Ye R, et al. Among authors: sorelle ja. J Clin Invest. 2018 Mar 1;128(3):1178-1189. doi: 10.1172/JCI97702. Epub 2018 Feb 19. J Clin Invest. 2018. PMID: 29457786 Free PMC article.
Mutual inhibition between Prkd2 and Bcl6 controls T follicular helper cell differentiation.
Misawa T, SoRelle JA, Choi JH, Yue T, Wang KW, McAlpine W, Wang J, Liu A, Tabeta K, Turer EE, Evers B, Nair-Gill E, Poddar S, Su L, Ou F, Yu L, Russell J, Ludwig S, Zhan X, Hildebrand S, Li X, Tang M, Murray AR, Moresco EMY, Beutler B. Misawa T, et al. Among authors: sorelle ja. Sci Immunol. 2020 Jan 24;5(43):eaaz0085. doi: 10.1126/sciimmunol.aaz0085. Sci Immunol. 2020. PMID: 31980486 Free PMC article.
Dominant atopy risk mutations identified by mouse forward genetic analysis.
SoRelle JA, Chen Z, Wang J, Yue T, Choi JH, Wang KW, Zhong X, Hildebrand S, Russell J, Scott L, Xu D, Zhan X, Bu CH, Wang T, Choi M, Tang M, Ludwig S, Zhan X, Li X, Moresco EMY, Beutler B. SoRelle JA, et al. Allergy. 2021 Apr;76(4):1095-1108. doi: 10.1111/all.14564. Epub 2020 Sep 20. Allergy. 2021. PMID: 32810290 Free PMC article.
Trans-Golgi protein TVP23B regulates host-microbe interactions via Paneth cell homeostasis and Goblet cell glycosylation.
Song R, McAlpine W, Fond AM, Nair-Gill E, Choi JH, Nyström EEL, Arike L, Field S, Li X, SoRelle JA, Moresco JJ, Moresco EMY, Yates JR 3rd, Azadi P, Ni J, Birchenough GMH, Beutler B, Turer EE. Song R, et al. Among authors: sorelle ja. Nat Commun. 2023 Jun 20;14(1):3652. doi: 10.1038/s41467-023-39398-1. Nat Commun. 2023. PMID: 37339972 Free PMC article.
OVOL2 sustains postnatal thymic epithelial cell identity.
Zhong X, Peddada N, Wang J, Moresco JJ, Zhan X, Shelton JM, SoRelle JA, Keller K, Lazaro DR, Moresco EMY, Choi JH, Beutler B. Zhong X, et al. Among authors: sorelle ja. Nat Commun. 2023 Nov 27;14(1):7786. doi: 10.1038/s41467-023-43456-z. Nat Commun. 2023. PMID: 38012144 Free PMC article.
Essential role of MFSD1-GLMP-GIMAP5 in lymphocyte survival and liver homeostasis.
Zhong X, Moresco JJ, Diedrich JK, Pinto AM, SoRelle JA, Wang J, Keller K, Ludwig S, Moresco EMY, Beutler B, Choi JH. Zhong X, et al. Among authors: sorelle ja. Proc Natl Acad Sci U S A. 2023 Dec 12;120(50):e2314429120. doi: 10.1073/pnas.2314429120. Epub 2023 Dec 6. Proc Natl Acad Sci U S A. 2023. PMID: 38055739 Free PMC article.
64 results