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Inhibition of nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme of the nicotinamide adenine dinucleotide (NAD) salvage pathway, to target glioma heterogeneity through mitochondrial oxidative stress.
Sharma P, Xu J, Williams K, Easley M, Elder JB, Lonser R, Lang FF, Lapalombella R, Sampath D, Puduvalli VK. Sharma P, et al. Among authors: lang ff. Neuro Oncol. 2022 Feb 1;24(2):229-244. doi: 10.1093/neuonc/noab175. Neuro Oncol. 2022. PMID: 34260721 Free PMC article.
Mechanisms of action of rapamycin in gliomas.
Heimberger AB, Wang E, McGary EC, Hess KR, Henry VK, Shono T, Cohen Z, Gumin J, Sawaya R, Conrad CA, Lang FF. Heimberger AB, et al. Among authors: lang ff. Neuro Oncol. 2005 Jan;7(1):1-11. doi: 10.1215/S1152851704000420. Neuro Oncol. 2005. PMID: 15701277 Free PMC article.
Phosphorylation of Thr18 and Ser20 of p53 in Ad-p53-induced apoptosis.
Nakamizo A, Amano T, Zhang W, Zhang XQ, Ramdas L, Liu TJ, Bekele BN, Shono T, Sasaki T, Benedict WF, Sawaya R, Lang FF. Nakamizo A, et al. Among authors: lang ff. Neuro Oncol. 2008 Jun;10(3):275-91. doi: 10.1215/15228517-2008-015. Epub 2008 Apr 28. Neuro Oncol. 2008. PMID: 18443131 Free PMC article.
Induction of cell-cycle arrest and apoptosis in glioblastoma stem-like cells by WP1193, a novel small molecule inhibitor of the JAK2/STAT3 pathway.
Sai K, Wang S, Balasubramaniyan V, Conrad C, Lang FF, Aldape K, Szymanski S, Fokt I, Dasgupta A, Madden T, Guan S, Chen Z, Alfred Yung WK, Priebe W, Colman H. Sai K, et al. Among authors: lang ff. J Neurooncol. 2012 May;107(3):487-501. doi: 10.1007/s11060-011-0786-z. Epub 2012 Jan 17. J Neurooncol. 2012. PMID: 22249692
Endoplasmic reticulum stress-inducing drugs sensitize glioma cells to temozolomide through downregulation of MGMT, MPG, and Rad51.
Xipell E, Aragón T, Martínez-Velez N, Vera B, Idoate MA, Martínez-Irujo JJ, Garzón AG, Gonzalez-Huarriz M, Acanda AM, Jones C, Lang FF, Fueyo J, Gomez-Manzano C, Alonso MM. Xipell E, et al. Among authors: lang ff. Neuro Oncol. 2016 Aug;18(8):1109-19. doi: 10.1093/neuonc/now022. Epub 2016 Mar 6. Neuro Oncol. 2016. PMID: 26951384 Free PMC article.
265 results