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The H3K36me2 writer-reader dependency in H3K27M-DIPG.
Yu JR, LeRoy G, Bready D, Frenster JD, Saldaña-Meyer R, Jin Y, Descostes N, Stafford JM, Placantonakis DG, Reinberg D. Yu JR, et al. Sci Adv. 2021 Jul 14;7(29):eabg7444. doi: 10.1126/sciadv.abg7444. Print 2021 Jul. Sci Adv. 2021. PMID: 34261657 Free PMC article.
Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma.
Stafford JM, Lee CH, Voigt P, Descostes N, Saldaña-Meyer R, Yu JR, Leroy G, Oksuz O, Chapman JR, Suarez F, Modrek AS, Bayin NS, Placantonakis DG, Karajannis MA, Snuderl M, Ueberheide B, Reinberg D. Stafford JM, et al. Among authors: yu jr. Sci Adv. 2018 Oct 31;4(10):eaau5935. doi: 10.1126/sciadv.aau5935. eCollection 2018 Oct. Sci Adv. 2018. PMID: 30402543 Free PMC article.
PRC2 is high maintenance.
Yu JR, Lee CH, Oksuz O, Stafford JM, Reinberg D. Yu JR, et al. Genes Dev. 2019 Aug 1;33(15-16):903-935. doi: 10.1101/gad.325050.119. Epub 2019 May 23. Genes Dev. 2019. PMID: 31123062 Free PMC article. Review.
305 results