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The B-cell Receptor Autoantigen LRPAP1 Can Replace Variable Antibody Regions to Target Mantle Cell Lymphoma Cells.
Bewarder M, Kiefer M, Will H, Olesch K, Moelle C, Stilgenbauer S, Christofyllakis K, Kaddu-Mulindwa D, Bittenbring JT, Fadle N, Regitz E, Kaschek L, Hoth M, Neumann F, Preuss KD, Pfreundschuh M, Thurner L. Bewarder M, et al. Among authors: thurner l. Hemasphere. 2021 Jul 13;5(8):e620. doi: 10.1097/HS9.0000000000000620. eCollection 2021 Aug. Hemasphere. 2021. PMID: 34263144 Free PMC article.
Progranulin antibodies in autoimmune diseases.
Thurner L, Preuss KD, Fadle N, Regitz E, Klemm P, Zaks M, Kemele M, Hasenfus A, Csernok E, Gross WL, Pasquali JL, Martin T, Bohle RM, Pfreundschuh M. Thurner L, et al. J Autoimmun. 2013 May;42:29-38. doi: 10.1016/j.jaut.2012.10.003. Epub 2012 Nov 11. J Autoimmun. 2013. PMID: 23149338
Proinflammatory progranulin antibodies in inflammatory bowel diseases.
Thurner L, Stöger E, Fadle N, Klemm P, Regitz E, Kemele M, Bette B, Held G, Dauer M, Lammert F, Preuss KD, Zimmer V, Pfreundschuh M. Thurner L, et al. Dig Dis Sci. 2014 Aug;59(8):1733-42. doi: 10.1007/s10620-014-3089-3. Epub 2014 Mar 4. Dig Dis Sci. 2014. PMID: 24591016
LRPAP1 is a frequent proliferation-inducing antigen of BCRs of mantle cell lymphomas and can be used for specific therapeutic targeting.
Thurner L, Hartmann S, Fadle N, Kemele M, Bock T, Bewarder M, Regitz E, Neumann F, Nimmesgern A, von Müller L, Pott C, Kim YJ, Bohle RM, Wasik M, Schuster SJ, Hansmann ML, Preuss KD, Pfreundschuh M. Thurner L, et al. Leukemia. 2019 Jan;33(1):148-158. doi: 10.1038/s41375-018-0182-1. Epub 2018 Jun 28. Leukemia. 2019. PMID: 29955130
Hyper-N-glycosylated SAMD14 and neurabin-I as driver autoantigens of primary central nervous system lymphoma.
Thurner L, Preuss KD, Bewarder M, Kemele M, Fadle N, Regitz E, Altmeyer S, Schormann C, Poeschel V, Ziepert M, Walter S, Roth P, Weller M, Szczepanowski M, Klapper W, Monoranu C, Rosenwald A, Möller P, Hartmann S, Hansmann ML, Mackensen A, Schäfer H, Schorb E, Illerhaus G, Buslei R, Bohle RM, Stilgenbauer S, Kim YJ, Pfreundschuh M. Thurner L, et al. Blood. 2018 Dec 27;132(26):2744-2753. doi: 10.1182/blood-2018-03-836932. Epub 2018 Sep 24. Blood. 2018. PMID: 30249786 Free article.
89 results