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Pre-vaccination and early B cell signatures predict antibody response to SARS-CoV-2 mRNA vaccine.
Kardava L, Rachmaninoff N, Lau WW, Buckner CM, Trihemasava K, de Assis FL, Wang W, Zhang X, Wang Y, Chiang CI, Narpala S, Reger R, McCormack GE, Seamon CA, Childs RW, Suffredini AF, Strich JR, Chertow DS, Davey RT, Sneller MC, O'Connell S, Li Y, McDermott A, Chun TW, Fauci AS, Tsang JS, Moir S. Kardava L, et al. Among authors: lau ww. medRxiv [Preprint]. 2021 Jul 7:2021.07.06.21259528. doi: 10.1101/2021.07.06.21259528. medRxiv. 2021. Update in: Proc Natl Acad Sci U S A. 2022 Jul 12;119(28):e2204607119. doi: 10.1073/pnas.2204607119 PMID: 34268520 Free PMC article. Updated. Preprint.
Post-infectious inflammatory disease in MIS-C features elevated cytotoxicity signatures and autoreactivity that correlates with severity.
Ramaswamy A, Brodsky NN, Sumida TS, Comi M, Asashima H, Hoehn KB, Li N, Liu Y, Shah A, Ravindra NG, Bishai J, Khan A, Lau W, Sellers B, Bansal N, Guerrerio P, Unterman A, Habet V, Rice AJ, Catanzaro J, Chandnani H, Lopez M, Kaminski N, Dela Cruz CS, Tsang JS, Wang Z, Yan X, Kleinstein SH, van Dijk D, Pierce RW, Hafler DA, Lucas CL. Ramaswamy A, et al. medRxiv [Preprint]. 2021 Apr 3:2020.12.01.20241364. doi: 10.1101/2020.12.01.20241364. medRxiv. 2021. Update in: Immunity. 2021 May 11;54(5):1083-1095.e7. doi: 10.1016/j.immuni.2021.04.003 PMID: 33300011 Free PMC article. Updated. Preprint.
Time-resolved systems immunology reveals a late juncture linked to fatal COVID-19.
Liu C, Martins AJ, Lau WW, Rachmaninoff N, Chen J, Imberti L, Mostaghimi D, Fink DL, Burbelo PD, Dobbs K, Delmonte OM, Bansal N, Failla L, Sottini A, Quiros-Roldan E, Han KL, Sellers BA, Cheung F, Sparks R, Chun TW, Moir S, Lionakis MS; NIAID COVID Consortium; COVID Clinicians; Rossi C, Su HC, Kuhns DB, Cohen JI, Notarangelo LD, Tsang JS. Liu C, et al. Among authors: lau ww. Cell. 2021 Apr 1;184(7):1836-1857.e22. doi: 10.1016/j.cell.2021.02.018. Epub 2021 Feb 10. Cell. 2021. PMID: 33713619 Free PMC article.
Immune dysregulation and autoreactivity correlate with disease severity in SARS-CoV-2-associated multisystem inflammatory syndrome in children.
Ramaswamy A, Brodsky NN, Sumida TS, Comi M, Asashima H, Hoehn KB, Li N, Liu Y, Shah A, Ravindra NG, Bishai J, Khan A, Lau W, Sellers B, Bansal N, Guerrerio P, Unterman A, Habet V, Rice AJ, Catanzaro J, Chandnani H, Lopez M, Kaminski N, Dela Cruz CS, Tsang JS, Wang Z, Yan X, Kleinstein SH, van Dijk D, Pierce RW, Hafler DA, Lucas CL. Ramaswamy A, et al. Immunity. 2021 May 11;54(5):1083-1095.e7. doi: 10.1016/j.immuni.2021.04.003. Epub 2021 Apr 13. Immunity. 2021. PMID: 33891889 Free PMC article.
Influenza vaccination and single cell multiomics reveal sex dimorphic immune imprints of prior mild COVID-19.
Sparks R, Lau WW, Liu C, Han KL, Vrindten KL, Sun G, Cox M, Andrews SF, Bansal N, Failla LE, Manischewitz J, Grubbs G, King LR, Koroleva G, Leimenstoll S, Snow L; OP11 Clinical Staff; Chen J, Tang J, Mukherjee A, Sellers BA, Apps R, McDermott AB, Martins AJ, Bloch EM, Golding H, Khurana S, Tsang JS. Sparks R, et al. Among authors: lau ww. medRxiv [Preprint]. 2022 Sep 1:2022.02.17.22271138. doi: 10.1101/2022.02.17.22271138. medRxiv. 2022. Update in: Nature. 2023 Feb;614(7949):752-761. doi: 10.1038/s41586-022-05670-5 PMID: 35233581 Free PMC article. Updated. Preprint.
Early human B cell signatures of the primary antibody response to mRNA vaccination.
Kardava L, Rachmaninoff N, Lau WW, Buckner CM, Trihemasava K, Blazkova J, Lopes de Assis F, Wang W, Zhang X, Wang Y, Chiang CI, Narpala S, McCormack GE, Liu C, Seamon CA, Sneller MC, O'Connell S, Li Y, McDermott AB, Chun TW, Fauci AS, Tsang JS, Moir S. Kardava L, et al. Among authors: lau ww. Proc Natl Acad Sci U S A. 2022 Jul 12;119(28):e2204607119. doi: 10.1073/pnas.2204607119. Epub 2022 Jun 27. Proc Natl Acad Sci U S A. 2022. PMID: 35759653 Free PMC article.
68 results