Akeno N - Search Results

1

Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity.

Pearson JD, Huang K, Pacal M, McCurdy SR, Lu S, Aubry A, Yu T, Wadosky KM, Zhang L, Wang T, Gregorieff A, Ahmad M, Dimaras H, Langille E, Cole SPC, Monnier PP, Lok BH, Tsao MS, Akeno N, Schramek D, Wikenheiser-Brokamp KA, Knudsen ES, Witkiewicz AK, Wrana JL, Goodrich DW, Bremner R. Pearson JD, et al. Among authors: akeno n. Cancer Cell. 2021 Aug 9;39(8):1115-1134.e12. doi: 10.1016/j.ccell.2021.06.016. Epub 2021 Jul 21. Cancer Cell. 2021. PMID: 34270926 Free PMC article.

2

p53 suppresses carcinoma progression by inhibiting mTOR pathway activation.

Akeno N, Miller AL, Ma X, Wikenheiser-Brokamp KA. Akeno N, et al. Oncogene. 2015 Jan 29;34(5):589-99. doi: 10.1038/onc.2013.589. Epub 2014 Jan 27. Oncogene. 2015. PMID: 24469052 Free PMC article.

3

TRP53 Mutants Drive Neuroendocrine Lung Cancer Through Loss-of-Function Mechanisms with Gain-of-Function Effects on Chemotherapy Response.

Akeno N, Reece AL, Callahan M, Miller AL, Kim RG, He D, Lane A, Moulton JS, Wikenheiser-Brokamp KA. Akeno N, et al. Mol Cancer Ther. 2017 Dec;16(12):2913-2926. doi: 10.1158/1535-7163.MCT-17-0353. Epub 2017 Aug 28. Mol Cancer Ther. 2017. PMID: 28847987 Free PMC article.

4

p16 controls epithelial cell growth and suppresses carcinogenesis through mechanisms that do not require RB1 function.

Sen M, Akeno N, Reece A, Miller AL, Simpson DS, Wikenheiser-Brokamp KA. Sen M, et al. Among authors: akeno n. Oncogenesis. 2017 Apr 17;6(4):e320. doi: 10.1038/oncsis.2017.5. Oncogenesis. 2017. PMID: 28414317 Free PMC article.

5

Osteoblast-specific expression of insulin-like growth factor-1 in bone of transgenic mice induces insulin-like growth factor binding protein-5.

Rutter MM, Markoff E, Clayton L, Akeno N, Zhao G, Clemens TL, Chernausek SD. Rutter MM, et al. Among authors: akeno n. Bone. 2005 Feb;36(2):224-31. doi: 10.1016/j.bone.2004.10.005. Bone. 2005. PMID: 15780948

6

RET/PTC-induced cell growth is mediated in part by epidermal growth factor receptor (EGFR) activation: evidence for molecular and functional interactions between RET and EGFR.

Croyle M, Akeno N, Knauf JA, Fabbro D, Chen X, Baumgartner JE, Lane HA, Fagin JA. Croyle M, et al. Among authors: akeno n. Cancer Res. 2008 Jun 1;68(11):4183-91. doi: 10.1158/0008-5472.CAN-08-0413. Cancer Res. 2008. PMID: 18519677 Free PMC article.

7

Hypoxia induces chondrocyte-specific gene expression in mesenchymal cells in association with transcriptional activation of Sox9.

Robins JC, Akeno N, Mukherjee A, Dalal RR, Aronow BJ, Koopman P, Clemens TL. Robins JC, et al. Among authors: akeno n. Bone. 2005 Sep;37(3):313-22. doi: 10.1016/j.bone.2005.04.040. Bone. 2005. PMID: 16023419

8

Induction of vascular endothelial growth factor by IGF-I in osteoblast-like cells is mediated by the PI3K signaling pathway through the hypoxia-inducible factor-2alpha.

Akeno N, Robins J, Zhang M, Czyzyk-Krzeska MF, Clemens TL. Akeno N, et al. Endocrinology. 2002 Feb;143(2):420-5. doi: 10.1210/endo.143.2.8639. Endocrinology. 2002. PMID: 11796494

9

BRAF mediates RET/PTC-induced mitogen-activated protein kinase activation in thyroid cells: functional support for requirement of the RET/PTC-RAS-BRAF pathway in papillary thyroid carcinogenesis.

Mitsutake N, Miyagishi M, Mitsutake S, Akeno N, Mesa C Jr, Knauf JA, Zhang L, Taira K, Fagin JA. Mitsutake N, et al. Among authors: akeno n. Endocrinology. 2006 Feb;147(2):1014-9. doi: 10.1210/en.2005-0280. Epub 2005 Oct 27. Endocrinology. 2006. PMID: 16254036

10

IFN-α mediates the development of autoimmunity both by direct tissue toxicity and through immune cell recruitment mechanisms.

Akeno N, Smith EP, Stefan M, Huber AK, Zhang W, Keddache M, Tomer Y. Akeno N, et al. J Immunol. 2011 Apr 15;186(8):4693-706. doi: 10.4049/jimmunol.1002631. Epub 2011 Mar 14. J Immunol. 2011. PMID: 21402899 Free PMC article.

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