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A SARS-CoV-2 neutralizing antibody selected from COVID-19 patients binds to the ACE2-RBD interface and is tolerant to most known RBD mutations.
Bertoglio F, Fühner V, Ruschig M, Heine PA, Abassi L, Klünemann T, Rand U, Meier D, Langreder N, Steinke S, Ballmann R, Schneider KT, Roth KDR, Kuhn P, Riese P, Schäckermann D, Korn J, Koch A, Chaudhry MZ, Eschke K, Kim Y, Zock-Emmenthal S, Becker M, Scholz M, Moreira GMSG, Wenzel EV, Russo G, Garritsen HSP, Casu S, Gerstner A, Roth G, Adler J, Trimpert J, Hermann A, Schirrmann T, Dübel S, Frenzel A, Van den Heuvel J, Čičin-Šain L, Schubert M, Hust M. Bertoglio F, et al. Among authors: trimpert j. Cell Rep. 2021 Jul 27;36(4):109433. doi: 10.1016/j.celrep.2021.109433. Epub 2021 Jul 7. Cell Rep. 2021. PMID: 34273271 Free PMC article.
Pet Rats as the Likely Reservoir for Human Seoul Orthohantavirus Infection.
Heuser E, Drewes S, Trimpert J, Kunec D, Mehl C, de Cock MP, de Vries A, Klier C, Oskamp M, Tenhaken P, Hashemi F, Heinz D, Nascimento M, Boelhauve M, Petraityte-Burneikiene R, Raafat D, Maas M, Krüger DH, Latz A, Hofmann J, Heckel G, Dreesman J, Ulrich RG. Heuser E, et al. Among authors: trimpert j. Viruses. 2023 Feb 7;15(2):467. doi: 10.3390/v15020467. Viruses. 2023. PMID: 36851681 Free PMC article.
A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model.
Kreye J, Reincke SM, Kornau HC, Sánchez-Sendin E, Corman VM, Liu H, Yuan M, Wu NC, Zhu X, Lee CD, Trimpert J, Höltje M, Dietert K, Stöffler L, von Wardenburg N, van Hoof S, Homeyer MA, Hoffmann J, Abdelgawad A, Gruber AD, Bertzbach LD, Vladimirova D, Li LY, Barthel PC, Skriner K, Hocke AC, Hippenstiel S, Witzenrath M, Suttorp N, Kurth F, Franke C, Endres M, Schmitz D, Jeworowski LM, Richter A, Schmidt ML, Schwarz T, Müller MA, Drosten C, Wendisch D, Sander LE, Osterrieder N, Wilson IA, Prüss H. Kreye J, et al. Among authors: trimpert j. Cell. 2020 Nov 12;183(4):1058-1069.e19. doi: 10.1016/j.cell.2020.09.049. Epub 2020 Sep 23. Cell. 2020. PMID: 33058755 Free PMC article.
Multi-species ELISA for the detection of antibodies against SARS-CoV-2 in animals.
Wernike K, Aebischer A, Michelitsch A, Hoffmann D, Freuling C, Balkema-Buschmann A, Graaf A, Müller T, Osterrieder N, Rissmann M, Rubbenstroth D, Schön J, Schulz C, Trimpert J, Ulrich L, Volz A, Mettenleiter T, Beer M. Wernike K, et al. Among authors: trimpert j. Transbound Emerg Dis. 2021 Jul;68(4):1779-1785. doi: 10.1111/tbed.13926. Epub 2020 Dec 10. Transbound Emerg Dis. 2021. PMID: 33191578 Free PMC article.
Development of safe and highly protective live-attenuated SARS-CoV-2 vaccine candidates by genome recoding.
Trimpert J, Dietert K, Firsching TC, Ebert N, Thi Nhu Thao T, Vladimirova D, Kaufer S, Labroussaa F, Abdelgawad A, Conradie A, Höfler T, Adler JM, Bertzbach LD, Jores J, Gruber AD, Thiel V, Osterrieder N, Kunec D. Trimpert J, et al. Cell Rep. 2021 Aug 3;36(5):109493. doi: 10.1016/j.celrep.2021.109493. Epub 2021 Jul 20. Cell Rep. 2021. PMID: 34320400 Free PMC article.
76 results