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Cyclic AMP analog blocks kinase activation by stabilizing inactive conformation: conformational selection highlights a new concept in allosteric inhibitor design.
Badireddy S, Yunfeng G, Ritchie M, Akamine P, Wu J, Kim CW, Taylor SS, Qingsong L, Swaminathan K, Anand GS. Badireddy S, et al. Among authors: ritchie m. Mol Cell Proteomics. 2011 Mar;10(3):M110.004390. doi: 10.1074/mcp.M110.004390. Epub 2010 Nov 16. Mol Cell Proteomics. 2011. PMID: 21081668 Free PMC article.
Author Correction: A deep catalogue of protein-coding variation in 983,578 individuals.
Sun KY, Bai X, Chen S, Bao S, Zhang C, Kapoor M, Backman J, Joseph T, Maxwell E, Mitra G, Gorovits A, Mansfield A, Boutkov B, Gokhale S, Habegger L, Marcketta A, Locke AE, Ganel L, Hawes A, Kessler MD, Sharma D, Staples J, Bovijn J, Gelfman S, Di Gioia A, Rajagopal VM, Lopez A, Varela JR, Alegre-Díaz J, Berumen J, Tapia-Conyer R, Kuri-Morales P, Torres J, Emberson J, Collins R; Regeneron Genetics Center; RGC-ME Cohort Partners; Cantor M, Thornton T, Kang HM, Overton JD, Shuldiner AR, Cremona ML, Nafde M, Baras A, Abecasis G, Marchini J, Reid JG, Salerno W, Balasubramanian S. Sun KY, et al. Nature. 2025 Jan 8. doi: 10.1038/s41586-024-08571-x. Online ahead of print. Nature. 2025. PMID: 39779867 No abstract available.
Rapid identification and phenotyping of nonalcoholic fatty liver disease patients using a machine-based approach in diverse healthcare systems.
Basile AO, Verma A, Tang LA, Serper M, Scanga A, Farrell A, Destin B, Carr RM, Anyanwu-Ofili A, Rajagopal G, Krikhely A, Bessler M, Reilly MP, Ritchie MD, Tatonetti NP, Wattacheril J. Basile AO, et al. Among authors: ritchie md. Clin Transl Sci. 2025 Jan;18(1):e70105. doi: 10.1111/cts.70105. Clin Transl Sci. 2025. PMID: 39739635 Free PMC article.
1,053 results