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An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography.
Butryn A, Simon PS, Aller P, Hinchliffe P, Massad RN, Leen G, Tooke CL, Bogacz I, Kim IS, Bhowmick A, Brewster AS, Devenish NE, Brem J, Kamps JJAG, Lang PA, Rabe P, Axford D, Beale JH, Davy B, Ebrahim A, Orlans J, Storm SLS, Zhou T, Owada S, Tanaka R, Tono K, Evans G, Owen RL, Houle FA, Sauter NK, Schofield CJ, Spencer J, Yachandra VK, Yano J, Kern JF, Orville AM. Butryn A, et al. Among authors: brem j. Nat Commun. 2021 Jul 22;12(1):4461. doi: 10.1038/s41467-021-24757-7. Nat Commun. 2021. PMID: 34294694 Free PMC article.
Assay platform for clinically relevant metallo-β-lactamases.
van Berkel SS, Brem J, Rydzik AM, Salimraj R, Cain R, Verma A, Owens RJ, Fishwick CW, Spencer J, Schofield CJ. van Berkel SS, et al. Among authors: brem j. J Med Chem. 2013 Sep 12;56(17):6945-53. doi: 10.1021/jm400769b. Epub 2013 Aug 16. J Med Chem. 2013. PMID: 23898798 Free PMC article.
93 results