Neikes H - Search Results

1

Simultaneous disruption of PRC2 and enhancer function underlies histone H3.3-K27M oncogenic activity in human hindbrain neural stem cells.

Brien GL, Bressan RB, Monger C, Gannon D, Lagan E, Doherty AM, Healy E, Neikes H, Fitzpatrick DJ, Deevy O, Grant V, Marqués-Torrejón MA, Alfazema N, Pollard SM, Bracken AP. Brien GL, et al. Among authors: neikes h. Nat Genet. 2021 Aug;53(8):1221-1232. doi: 10.1038/s41588-021-00897-w. Epub 2021 Jul 22. Nat Genet. 2021. PMID: 34294917

2

PRC2.1 and PRC2.2 Synergize to Coordinate H3K27 Trimethylation.

Healy E, Mucha M, Glancy E, Fitzpatrick DJ, Conway E, Neikes HK, Monger C, Van Mierlo G, Baltissen MP, Koseki Y, Vermeulen M, Koseki H, Bracken AP. Healy E, et al. Among authors: neikes hk. Mol Cell. 2019 Nov 7;76(3):437-452.e6. doi: 10.1016/j.molcel.2019.08.012. Epub 2019 Sep 11. Mol Cell. 2019. PMID: 31521505 Free article.

3

Retinoic acid signaling drives differentiation toward the absorptive lineage in colorectal cancer.

Wester RA, van Voorthuijsen L, Neikes HK, Dijkstra JJ, Lamers LA, Frölich S, van der Sande M, Logie C, Lindeboom RGH, Vermeulen M. Wester RA, et al. Among authors: neikes hk. iScience. 2021 Nov 15;24(12):103444. doi: 10.1016/j.isci.2021.103444. eCollection 2021 Dec 17. iScience. 2021. PMID: 34877501 Free PMC article.

4

Quantifying genome-wide transcription factor binding affinities for chromatin using BANC-seq.

Wester RA, Neikes HK, Lindeboom RGH, Vermeulen M. Wester RA, et al. Among authors: neikes hk. Nat Protoc. 2024 Dec;19(12):3590-3612. doi: 10.1038/s41596-024-01026-7. Epub 2024 Jul 30. Nat Protoc. 2024. PMID: 39080437 Review.

5

PRC2.1- and PRC2.2-specific accessory proteins drive recruitment of different forms of canonical PRC1.

Glancy E, Wang C, Tuck E, Healy E, Amato S, Neikes HK, Mariani A, Mucha M, Vermeulen M, Pasini D, Bracken AP. Glancy E, et al. Among authors: neikes hk. Mol Cell. 2023 May 4;83(9):1393-1411.e7. doi: 10.1016/j.molcel.2023.03.018. Epub 2023 Apr 7. Mol Cell. 2023. PMID: 37030288 Free PMC article.

6

Quantification of absolute transcription factor binding affinities in the native chromatin context using BANC-seq.

Neikes HK, Kliza KW, Gräwe C, Wester RA, Jansen PWTC, Lamers LA, Baltissen MP, van Heeringen SJ, Logie C, Teichmann SA, Lindeboom RGH, Vermeulen M. Neikes HK, et al. Nat Biotechnol. 2023 Dec;41(12):1801-1809. doi: 10.1038/s41587-023-01715-w. Epub 2023 Mar 27. Nat Biotechnol. 2023. PMID: 36973556

7

Genetic screens reveal new targetable vulnerabilities in BAP1-deficient mesothelioma.

Pandey GK, Landman N, Neikes HK, Hulsman D, Lieftink C, Beijersbergen R, Kolluri KK, Janes SM, Vermeulen M, Badhai J, van Lohuizen M. Pandey GK, et al. Among authors: neikes hk. Cell Rep Med. 2023 Feb 21;4(2):100915. doi: 10.1016/j.xcrm.2022.100915. Epub 2023 Jan 18. Cell Rep Med. 2023. PMID: 36657447 Free PMC article.

8

ONECUT2 regulates RANKL-dependent enterocyte and microfold cell differentiation in the small intestine; a multi-omics study.

Luna Velez MV, Neikes HK, Snabel RR, Quint Y, Qian C, Martens A, Veenstra GJC, Freeman MR, van Heeringen SJ, Vermeulen M. Luna Velez MV, et al. Among authors: neikes hk. Nucleic Acids Res. 2023 Feb 22;51(3):1277-1296. doi: 10.1093/nar/gkac1236. Nucleic Acids Res. 2023. PMID: 36625255 Free PMC article.

9

Multiomics of Colorectal Cancer Organoids Reveals Putative Mediators of Cancer Progression Resulting from SMAD4 Inactivation.

Dijkstra JJ, Neikes HK, Rezaeifard S, Ma X, Voest EE, Tauriello DVF, Vermeulen M. Dijkstra JJ, et al. Among authors: neikes hk. J Proteome Res. 2023 Jan 6;22(1):138-151. doi: 10.1021/acs.jproteome.2c00551. Epub 2022 Nov 30. J Proteome Res. 2023. PMID: 36450103 Free PMC article.

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