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Page 1
Molecular basis of agonist docking in a human GPR103 homology model by site-directed mutagenesis and structure-activity relationship studies.
Neveu C, Dulin F, Lefranc B, Galas L, Calbrix C, Bureau R, Rault S, Chuquet J, Boutin JA, Guilhaudis L, Ségalas-Milazzo I, Vaudry D, Vaudry H, Santos JS, Leprince J. Neveu C, et al. Among authors: chuquet j. Br J Pharmacol. 2014 Oct;171(19):4425-39. doi: 10.1111/bph.12808. Epub 2014 Sep 5. Br J Pharmacol. 2014. PMID: 24913445 Free PMC article.
Design, Synthesis, Molecular Dynamics Simulation, and Functional Evaluation of a Novel Series of 26RFa Peptide Analogues Containing a Mono- or Polyalkyl Guanidino Arginine Derivative.
Alim K, Lefranc B, Sopkova-de Oliveira Santos J, Dubessy C, Picot M, Boutin JA, Vaudry H, Chartrel N, Vaudry D, Chuquet J, Leprince J. Alim K, et al. Among authors: chuquet j. J Med Chem. 2018 Nov 21;61(22):10185-10197. doi: 10.1021/acs.jmedchem.8b01332. Epub 2018 Nov 7. J Med Chem. 2018. PMID: 30358997
Rational design of a low molecular weight, stable, potent, and long-lasting GPR103 aza-β3-pseudopeptide agonist.
Neveu C, Lefranc B, Tasseau O, Do-Rego JC, Bourmaud A, Chan P, Bauchat P, Le Marec O, Chuquet J, Guilhaudis L, Boutin JA, Ségalas-Milazzo I, Costentin J, Vaudry H, Baudy-Floc'h M, Vaudry D, Leprince J. Neveu C, et al. Among authors: chuquet j. J Med Chem. 2012 Sep 13;55(17):7516-24. doi: 10.1021/jm300507d. Epub 2012 Aug 17. J Med Chem. 2012. PMID: 22800498
Endozepines and their receptors: Structure, functions and pathophysiological significance.
Tonon MC, Vaudry H, Chuquet J, Guillebaud F, Fan J, Masmoudi-Kouki O, Vaudry D, Lanfray D, Morin F, Prevot V, Papadopoulos V, Troadec JD, Leprince J. Tonon MC, et al. Among authors: chuquet j. Pharmacol Ther. 2020 Apr;208:107386. doi: 10.1016/j.pharmthera.2019.06.008. Epub 2019 Jul 5. Pharmacol Ther. 2020. PMID: 31283949 Review.
Cytoprotective and Neurotrophic Effects of Octadecaneuropeptide (ODN) in in vitro and in vivo Models of Neurodegenerative Diseases.
Masmoudi-Kouki O, Namsi A, Hamdi Y, Bahdoudi S, Ghouili I, Chuquet J, Leprince J, Lefranc B, Ghrairi T, Tonon MC, Lizard G, Vaudry D. Masmoudi-Kouki O, et al. Among authors: chuquet j. Front Endocrinol (Lausanne). 2020 Nov 4;11:566026. doi: 10.3389/fendo.2020.566026. eCollection 2020. Front Endocrinol (Lausanne). 2020. PMID: 33250858 Free PMC article. Review.
The Gliopeptide ODN, a Ligand for the Benzodiazepine Site of GABAA Receptors, Boosts Functional Recovery after Stroke.
Lamtahri R, Hazime M, Gowing EK, Nagaraja RY, Maucotel J, Alasoadura M, Quilichini PP, Lehongre K, Lefranc B, Gach-Janczak K, Marcher AB, Mandrup S, Vaudry D, Clarkson AN, Leprince J, Chuquet J. Lamtahri R, et al. Among authors: chuquet j. J Neurosci. 2021 Aug 18;41(33):7148-7159. doi: 10.1523/JNEUROSCI.2255-20.2021. Epub 2021 Jul 1. J Neurosci. 2021. PMID: 34210784 Free PMC article.
Neuroprotective effects of the gliopeptide ODN in an in vivo model of Parkinson's disease.
Bahdoudi S, Ghouili I, Hmiden M, do Rego JL, Lefranc B, Leprince J, Chuquet J, do Rego JC, Marcher AB, Mandrup S, Vaudry H, Tonon MC, Amri M, Masmoudi-Kouki O, Vaudry D. Bahdoudi S, et al. Among authors: chuquet j. Cell Mol Life Sci. 2018 Jun;75(11):2075-2091. doi: 10.1007/s00018-017-2727-2. Epub 2017 Dec 20. Cell Mol Life Sci. 2018. PMID: 29264673 Free PMC article.
Detection, characterization and biological activities of [bisphospho-thr3,9]ODN, an endogenous molecular form of ODN released by astrocytes.
Gach K, Belkacemi O, Lefranc B, Perlikowski P, Masson J, Walet-Balieu ML, Do-Rego JC, Galas L, Schapman D, Lamtahri R, Tonon MC, Vaudry D, Chuquet J, Leprince J. Gach K, et al. Among authors: chuquet j. Neuroscience. 2015 Apr 2;290:472-84. doi: 10.1016/j.neuroscience.2015.01.045. Epub 2015 Jan 30. Neuroscience. 2015. PMID: 25639232
22 results